Capillary density: An important parameter in nailfold capillaroscopy

被引:65
作者
Emrani, Zahra [1 ]
Karbalaie, Abdolamir [2 ]
Fatemi, Alimohammad [3 ]
Etehadtavakol, Mahnaz [1 ]
Erlandsson, Bjorn-Erik [2 ]
机构
[1] Isfahan Univ Med Sci, Med Image & Signal Proc Res Ctr, Esfahan, Iran
[2] Royal Inst Technol KTH, Sch Technol & Hlth, SE-10044 Stockholm, Sweden
[3] Isfahan Univ Med Sci, Alzahra Hosp, Dept Rheumatol, Esfahan, Iran
关键词
Nailfold capillaroscopy; Capillary density; Antinuclear antibodies; Digital ulcer; Pulmonary arterial hypertension; SYSTEMIC-SCLEROSIS PATIENTS; PULMONARY ARTERIAL-HYPERTENSION; CHILDHOOD RHEUMATIC-DISEASES; ULCER RISK INDEX; RAYNAUDS-PHENOMENON; DIGITAL ULCERS; MICROVASCULAR CHANGES; PREDICTIVE FACTORS; LASER-DOPPLER; VIDEOCAPILLAROSCOPIC PATTERNS;
D O I
10.1016/j.mvr.2016.09.001
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Nailfold capillaroscopy is one of the various noninvasive bioengineering methods used to investigate skin micro circulation. It is an effective examination for assessing microvascular changes in the peripheral circulation; hence it has a significant role for the diagnosis of Systemic sclerosis with the classic changes of giant capillaries as well as the decline in capillary density with capillary dropout. The decline in capillary density is one of microangiopathic features existing in connective tissue disease. It is detectable with nailfold capillaroscopy. This parameter is assessed by applying quantitative measurement. In this article, we reviewed a common method for calculating the capillary density and the relation between the number of capillaries as well as the existence of digital ulcers, pulmonary arterial hypertension, autoantibodies, scleroderma patterns and different scoring system. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:7 / 18
页数:12
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