Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin

被引:43
作者
Chobot, Vladimir [1 ]
Hadacek, Franz [2 ]
Bachmann, Gert [1 ]
Weckwerth, Wolfram [1 ]
Kubicova, Lenka [1 ]
机构
[1] Univ Vienna, Fac Life Sci, Dept Ecogenom & Syst Biol, Div Mol Syst Biol, Althanstr 14, A-1090 Vienna, Austria
[2] Georg August Univ Gottingen, Albrecht von Haller Inst, Dept Plant Biochem, Justus von Liebig Weg 11, D-37077 Gottingen, Germany
基金
奥地利科学基金会;
关键词
flavonoids; redox chemistry; differential pulse voltammetry; deoxyribose degradation assay; Fenton reaction; ELECTROCHEMICAL OXIDATION MECHANISMS; PHENOLIC-COMPOUNDS; LIPID-PEROXIDATION; CYCLIC VOLTAMMETRY; PROOXIDANT; DEOXYRIBOSE; POLYPHENOLS; OXIDANTS; ACIDS; ASSAY;
D O I
10.3390/ijms17121986
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The flavanol (+/-)-catechin shows an OH group but no 4-keto group on ring C (C3), and no conjugation between ring A and B. The related flavanone (+)-eriodictyol has a keto group on C4 but no 3-OH group on ring C. (+)-Taxifolin, another flavanone, has an OH on C3 and a keto group on C4 of the C ring. Deoxyribose degradation assay systems, with hydrogen peroxide and ascorbic acid either added or omitted, were performed in variants in which Fe(III) was added in a complex with ethylenediaminetetraacetic acid (EDTA). In combination with differential pulse voltammetry (DVP), the specific redox-chemical contributions of the ring A m-dihydroxyl groups could be explored more specifically in addition to those of the traditionally investigated o-dihydroxyl groups of ring B.
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页数:9
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