The Pivotal Role of FDG-PET/CT in Modern Medicine

被引:100
作者
Hess, Soren [1 ]
Blomberg, Bjorn A. [1 ,2 ]
Zhu, Hongyun June [3 ]
Hoilund-Carlsen, Poul Flemming [1 ]
Alavi, Abass [4 ]
机构
[1] Odense Univ Hosp, Dept Nucl Med, DK-5000 Odense, Denmark
[2] Univ Med Ctr Utrecht, Dept Radiol & Nucl Med, Utrecht, Netherlands
[3] Univ Arkansas Med Sci, Dept Radiol, Little Rock, AR 72205 USA
[4] Univ Penn, Perelman Sch Med, Hosp Univ Penn, Div Nucl Med, Philadelphia, PA 19104 USA
关键词
Positron emission tomography/computed tomography; PET/CT; 2-deoxy-2-[18F]fluoro-D-glucose; FDG; molecular imaging; POSITRON-EMISSION-TOMOGRAPHY; DUAL-TIME-POINT; ATHEROSCLEROTIC PLAQUE INFLAMMATION; F-18 FLUORODEOXYGLUCOSE UPTAKE; VASCULAR INFLAMMATION; IMAGING TECHNIQUES; HIBERNATING MYOCARDIUM; UNDERLYING MALIGNANCY; RHEUMATOID-ARTHRITIS; ALZHEIMERS-DISEASE;
D O I
10.1016/j.acra.2013.11.002
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The technology behind positron emission tomography (PET) and the most widely used tracer, 2-deoxy-2[18F]fluoro-D-glucose (FDG), were both conceived in the 1970s, but the latest decade has witnessed a rapid emergence of FDG-PET as an effective imaging technique. This is not least due to the emergence of hybrid scanners combining PET with computed tomography (PET/CT). Molecular imaging has enormous potential for advancing biological research and patient care, and FDG-PET/CT is currently the most widely used technology in this domain. In this review, we discuss contemporary applications of FDG-PET and FDG-PET/CT as well as novel developments in quantification and potential future indications including the emerging new modality PET/magnetic resonance imaging.
引用
收藏
页码:232 / 249
页数:18
相关论文
共 154 条
[61]   PET/CT imaging in infectious conditions [J].
Israel, Ora ;
Keidar, Zohar .
PET/CT APPLICATIONS IN NON-NEOPLASTIC CONDITIONS, 2011, 1228 :150-166
[62]  
Israel-Biet D, 2013, CURR OPIN PULM MED
[63]   FDG PET/CT imaging in the diagnosis of osteomyelitis in the diabetic foot [J].
Kagna, Olga ;
Srour, Saher ;
Melamed, Eyal ;
Militianu, Daniela ;
Keidar, Zohar .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2012, 39 (10) :1545-1550
[64]   An introduction to PET-CT imaging [J].
Kapoor, V ;
McCook, BM ;
Torok, FS .
RADIOGRAPHICS, 2004, 24 (02) :523-543
[65]  
Kepe V, 2013, J ALZHEIMERS DIS
[66]   Vascular Inflammation in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Analysis With 18F-Fluorodeoxyglucose Positron Emission Tomography [J].
Kim, Tae Nyun ;
Kim, Sungeun ;
Yang, Sae Jeong ;
Yoo, Hye Jin ;
Seo, Ji A. ;
Kim, Sin Gon ;
Kim, Nan Hee ;
Baik, Sei Hyun ;
Choi, Dong Seop ;
Choi, Kyung Mook .
CIRCULATION-CARDIOVASCULAR IMAGING, 2010, 3 (02) :142-148
[67]   Diagnostic value of positron emission tomography combined with computed tomography for evaluating patients with septic shock of unknown origin [J].
Kluge, Stefan ;
Braune, Stephan ;
Nierhaus, Axel ;
Wichmann, Dominic ;
Derlin, Thorsten ;
Mester, Janos ;
Klutmann, Susanne .
JOURNAL OF CRITICAL CARE, 2012, 27 (03) :316.e1-316.e7
[68]   Fever of unknown origin in adults: 40 years on [J].
Knockaert, DC ;
Vanderschueren, S ;
Blockmans, D .
JOURNAL OF INTERNAL MEDICINE, 2003, 253 (03) :263-275
[69]   FDG PET for rheumatoid arthritis: basic considerations and whole-body PET/CT [J].
Kubota, Kazuo ;
Ito, Kimiteru ;
Morooka, Miyako ;
Minamimoto, Ryogo ;
Miyata, Yuko ;
Yamashita, Hiroyuki ;
Takahashi, Yuko ;
Mimori, Akio .
PET/CT APPLICATIONS IN NON-NEOPLASTIC CONDITIONS, 2011, 1228 :29-38
[70]  
Kumar R, 2005, J NUCL MED, V46, P1819