Subcutaneous panniculitis-like T cell lymphoma with mesenteric involvement

Subcutaneous panniculitis-like T cell lymphoma (SPTCL) is a rare type of lymphoma, which is characterized by distinctive rimming of neoplastic lymphocytes surrounding individual adipocytes in subcutaneous tissue. SPTCL is confined to subcutis and dissemination of SPTCL to extracutaneous sites is extremely rare, if present at all. Here we present a case of SPTCL with mesenteric involvement. The patient initially presented with a solitary skin lesion at the lower extremity. A few months later, he developed new skin lesions at the abdominal wall and mesenteric lesions in the abdominal cavity. Biopsy showed SPTCL in subcutaneous tissue with mesenteric involvement. To our knowledge, this is the first case report of pathologically proven dissemination of SPTCL to other sites.