One pot synthesis of selenocysteine containing peptoid libraries by Ugi multicomponent reactions in water

被引：42
作者：
Abbas, M [1 ]
Bethke, J [1 ]
Wessjohann, LA [1 ]
机构：
[1] Leibniz Inst Plant Biochem, Dept Bioorgan Chem, D-06120 Halle, Germany
来源：
CHEMICAL COMMUNICATIONS | 2006年 / 05期
关键词：
D O I：
10.1039/b514597j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Selenocysteine containing peptoids and peptide-peptoid conjugates were synthesized by combinatorial Ugi-MCRs (multicomponent reactions) in water: for the first time, an acetal (selenoacetal 2a) was used in Ugi-MCR to furnish selenocysteine peptoids in one step as model compounds for selenocysteine peptides and proteins.
引用
收藏
页码：541 / 543
页数：3
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