Comparative Analysis of Allergic Rhinitis in Children and Adults

被引:66
作者
Izquierdo-Dominguez, Adriana [1 ]
Valero, Antonio L. [2 ,3 ]
Mullol, Joaquim [3 ,4 ,5 ,6 ,7 ]
机构
[1] Hosp Quiron, Dept Allergol, Barcelona, Catalonia, Spain
[2] Hosp Clin & Univ, Inst Invest Biomed August Pi & Sunyer IDIBAPS, ICT, Dept Pneumol & Resp Allergy, Barcelona, Catalonia, Spain
[3] CIBER Enfermedades Resp CIBERES, Barcelona, Catalonia, Spain
[4] Hosp Clin & Univ, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Dept Otorhinolaryngol, Rhinol Unit, Barcelona, Catalonia, Spain
[5] Hosp Clin & Univ, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Dept Otorhinolaryngol, Smell Clin, Barcelona, Catalonia, Spain
[6] IDIBAPS, Hosp Clin, Dept Otorhinolaryngol, Rhinol Unit, Barcelona 08036, Catalonia, Spain
[7] IDIBAPS, Hosp Clin, Dept Otorhinolaryngol, Smell Clin, Barcelona 08036, Catalonia, Spain
关键词
Allergic rhinitis; Adults; Children; Epidemiology; Quality of life; Management; Clinical features; Comparative analysis; Prevalence; Classification; Immunotherapy; QUALITY-OF-LIFE; CHILDHOOD ISAAC; WORLDWIDE VARIATIONS; NASAL SYMPTOMS; UNITED-STATES; ASTHMA; PREVALENCE; IMPACT; SEVERITY; POPULATION;
D O I
10.1007/s11882-012-0331-y
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Allergic rhinitis (AR) is a worldwide health problem that generates a significant healthcare burden in adults, adolescents, and children. Epidemiological studies have indicated that the prevalence of AR has progressively increased over the last three decades in developed and industrialized countries. AR currently affects up to 40 % of the worldwide population, with differences between adults and children and different countries of the World. Although not life-threatening, AR symptoms are frequently bothersome, adversely affecting work and quality of life of the affected patients, and causing a significant burden on both the individual and society. The symptoms have the potential to lead to both physical and mental complications, with sleep-disordered breathing in childhood and adolescence being associated with disorders in learning performance, behavior, and attention. Clinical features and comorbidities are very important for the "allergic march", and in both adults and children there is some evidence of association between AR and asthma. ARIA classifications of both symptom duration (intermittent, persistent) and severity (mild, moderate, severe) have been validated in both adult and pediatric populations. Based on the duration and severity of patient's disease, an appropriate treatment strategy has been issued for both adults and children, which consists of patient's education, allergen avoidance, and pharmacological as well as allergen-specific immunotherapy treatment. The present review will attempt to compare the characteristics of AR between children and adults, either in the epidemiology, clinical features, impact on QOL, and management of the disease.
引用
收藏
页码:142 / 151
页数:10
相关论文
共 75 条
[41]   Development of seasonal allergic rhinitis during the first 7 years of life [J].
Kulig, M ;
Klettke, U ;
Wahn, V ;
Forster, J ;
Bauer, CP ;
Wahn, U .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 106 (05) :832-839
[42]   The role of indoor allergen sensitization and exposure in causing morbidity in women with asthma [J].
Lewis, SA ;
Weiss, ST ;
Platts-Mills, TAE ;
Burge, H ;
Gold, DR .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (07) :961-966
[43]  
Marinho Susana, 2006, Prim Care Respir J, V15, P152, DOI 10.1016/j.pcrj.2006.02.005
[44]   Burden of allergic rhinitis: Results from the Pediatric Allergies in America survey [J].
Meltzer, Eli O. ;
Blaiss, Michael S. ;
Derebery, M. Jennifer ;
Mahr, Todd A. ;
Gordon, Bruce R. ;
Sheth, Ketan K. ;
Simmons, A. Larry ;
Wingertzahn, Mark A. ;
Boyle, John M. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 124 (03) :S43-S70
[45]   Validation of the modified allergic rhinitis and its impact on asthma (ARIA) severity classification in allergic rhinitis children: the PEDRIAL study [J].
Montoro, J. ;
Del Cuvillo, A. ;
Mullol, J. ;
Molina, X. ;
Bartra, J. ;
Davila, I. ;
Ferrer, M. ;
Jauregui, I. ;
Sastre, J. ;
Valero, A. .
ALLERGY, 2012, 67 (11) :1437-1442
[46]   Risk factors for asthma symptoms at school age: An 8-year prospective study [J].
Morais-Almeida, Marco ;
Gaspar, Angola ;
Pires, Graqa ;
Prates, Sara ;
Rosacto-Pinto, Jose .
ALLERGY AND ASTHMA PROCEEDINGS, 2007, 28 (02) :183-189
[47]  
Mullol J, 2009, J INVEST ALLERG CLIN, V19, P27
[48]   The burden of allergic rhinitis [J].
Nathan, Robert A. .
ALLERGY AND ASTHMA PROCEEDINGS, 2007, 28 (01) :3-9
[49]   The prevalence of nasal symptoms attributed to allergies in the United States: Findings from the burden of rhinitis in an America survey [J].
Nathan, Robert A. ;
Meltzer, Eli O. ;
Derebery, Jennifer ;
Campbell, Ulka B. ;
Stang, Paul E. ;
Corrao, Marlo A. ;
Allen, Gina ;
Stanford, Richard .
ALLERGY AND ASTHMA PROCEEDINGS, 2008, 29 (06) :600-608
[50]   Nasal allergies in the Latin American population: Results from the Allergies in Latin America survey [J].
Neffen, Hugo ;
Mello, Joao F., Jr. ;
Sole, Dirceu ;
Naspitz, Charles K. ;
Eduardo Dodero, Alberto ;
Leon Garza, Hector ;
Novelo Guerra, Edgard ;
Baez-Loyola, Carlos ;
Boyle, John M. ;
Wingertzahn, Mark A. .
ALLERGY AND ASTHMA PROCEEDINGS, 2010, 31 (03) :S9-S27