Development of a sensitive method for quantitation of DNA pyridyloxobutylation adducts derived from the tobacco specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

被引:0
|
作者
Lao, YB
Villalta, PW
Wang, MY
Cheng, G
Sturla, SJ
Hecht, SS
机构
[1] Univ Minnesota, Dept Med Chem, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Ctr Canc, Minneapolis, MN 55455 USA
关键词
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
39
引用
收藏
页码:1974 / 1974
页数:1
相关论文
共 50 条
  • [21] Oxidative DNA damage in tissues of pregnant female mice and fetuses caused by the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
    Sipowicz, MA
    Amin, S
    Desai, D
    Kasprzak, KS
    Anderson, LM
    CANCER LETTERS, 1997, 117 (01) : 87 - 91
  • [22] Contribution of Tobacco Use and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone to Three Methyl DNA Adducts in Urine
    Wang, Yi
    Narayanapillai, Sreekanth
    Hu, Qi
    Fujioka, Naomi
    Xing, Chengguo
    CHEMICAL RESEARCH IN TOXICOLOGY, 2018, 31 (09) : 836 - 838
  • [23] Kava Effects on the Metabolism of Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK) in Humans
    Oostra, Drew
    Fujioka, Naomi
    Xing, Chengguo
    Narayanapillai, Sreekanth
    Paladino, Jordan
    Alves, Hannah
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S455 - S455
  • [24] Racial differences in exposure and glucuronidation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
    Muscat, JE
    Djordjevic, MV
    Colosimo, S
    Stellman, SD
    Richie, JP
    CANCER, 2005, 103 (07) : 1420 - 1426
  • [25] Metabolism and disposition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in rhesus monkeys
    Meger, M
    Richter, E
    Zwickenpflug, W
    Oehlmann, C
    Hargaden, MB
    A-Rahim, YI
    Vesell, ES
    DRUG METABOLISM AND DISPOSITION, 1999, 27 (04) : 471 - 478
  • [26] Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes
    Collazo, NR
    Sultatos, LG
    BIOCHEMICAL PHARMACOLOGY, 1995, 50 (11) : 1933 - 1941
  • [27] INVIVO AND INVITRO PERSISTENCE OF PYRIDYLOXOBUTYL DNA ADDUCTS FROM 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE
    PETERSON, LA
    MATHEW, R
    MURPHY, SE
    TRUSHIN, N
    HECHT, SS
    CARCINOGENESIS, 1991, 12 (11) : 2069 - 2072
  • [28] Synthesis and in vivo quantitation of 2′-deoxyadenosine adducts resulting from bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol
    Carlson, Erik
    Upadhyaya, Pramod
    Hecht, Stephen
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [29] Adsorption of tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone from aqueous solution with graphene aerogel
    Xu, T. G.
    Shi, R.
    Lu, N.
    Zhang, J.
    Bai, R. S.
    Yang, Z. D.
    Zhou, J.
    2017 5TH INTERNATIONAL CONFERENCE ON MECHANICAL ENGINEERING, MATERIALS SCIENCE AND CIVIL ENGINEERING, 2018, 324
  • [30] INVESTIGATIONS OF METABOLIC PRECURSORS TO HEMOGLOBIN AND DNA ADDUCTS OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE
    PETERSON, LA
    CARMELLA, SG
    HECHT, SS
    CARCINOGENESIS, 1990, 11 (08) : 1329 - 1333