Thermogelation Properties of ABA Triblock Copolymers of Poly(Ethylene Glycol) (B) and Copolyacrylates of Oligo(Ethylene Glycol)s (A) in Aqueous Solution

被引：10
作者：
Negru, Ioana [1 ]
Teodorescu, Mircea [1 ]
Stanescu, Paul O. [1 ]
Draghici, Constantin [2 ]
Lungu, Anamaria [3 ]
Sarbu, Andrei [3 ]
机构：
[1] Polytech Univ, Dept Polymer Sci & Engn, Bucharest 010072, Romania
[2] Romanian Acad, Ctr Organ Chem, Bucharest, Romania
[3] Natl Inst Res & Dev Chem & Petrochem ICECHIM, Dept Polymers, Bucharest, Romania
来源：
SOFT MATERIALS | 2013年 / 11卷 / 02期
关键词：
ATRP; Di(ethylene glycol) ethyl ether acrylate; Oligo(ethylene glycol) methyl ether acrylate; Poly(ethylene glycol); Thermal gelation; Thermoresponsive hydrogels; Triblock copolymers; THERMAL GELATION PROPERTIES; CONTROLLED DRUG-DELIVERY; RESPONSIVE POLYMERS; HYDROGELS; POLY(N-ISOPROPYLACRYLAMIDE); METHACRYLATE; DESIGN; BLOCK; GELS;
D O I：
10.1080/1539445X.2011.597816
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Novel triblock copolymers with poly(ethylene glycol) (PEG) middle chain and random copolymers of di(ethylene glycol) ethyl ether acrylate (DEGA) and oligo(ethylene glycol) methyl ether acrylate (OEGA) as side blocks were synthesized by ATRP. The thermal gelation behavior of their 20 wt% aqueous solutions was studied as a function of the molecular characteristics of the triblock copolymers. The results showed that both association and gelation temperatures decreased with increasing polymerization degree and decreasing OEGA monomer content of the polyacrylate block. Also, both temperatures increased with PEG length at smaller MW of the PEG chain, and decreased for higher MW PEG. Rheometrical measurements showed that the length of the PEG block is the most important factor influencing elastic modulus and even structure of the hydrogels formed at 37 degrees C. [Supplementary materials are available for this article. Go to the publisher's online edition of Soft Materials for the following free supplemental resource(s): Supplementary material.doc]
引用
收藏
页码：149 / 156
页数：8
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