Primary cerebellar histiocytic sarcoma in a 17-month-old girl Case report

被引：14

作者：

Gomi, Kiyoshi ^{[1
]}

Tanaka, Mio

Yoshida, Mariko

Ito, Susumu ^{[2
]}

Sonoda, Masaki ^{[2
]}

Iwasaki, Fuminori ^{[3
]}

Niwa, Tetsu ^{[4
]}

Aida, Noriko ^{[4
]}

Kigasawa, Hisato ^{[3
]}

Tanaka, Yukichi

机构：

[1] Kanagawa Childrens Med Ctr, Div Pathol, Minami Ku, Yokohama, Kanagawa 2328555, Japan

[2] Kanagawa Childrens Med Ctr, Div Neurosurg, Yokohama, Kanagawa 2328555, Japan

[3] Kanagawa Childrens Med Ctr, Div Oncol, Yokohama, Kanagawa 2328555, Japan

[4] Kanagawa Childrens Med Ctr, Div Radiol, Yokohama, Kanagawa 2328555, Japan

来源：

JOURNAL OF NEUROSURGERY-PEDIATRICS | 2012年 / 10卷 / 02期

关键词：

histiocytic sarcoma; cerebellum; pediatric; oncology; CENTRAL-NERVOUS-SYSTEM; OF-THE-LITERATURE; LYMPHOMA; CHILDHOOD; INFANCY; TUMORS;

D O I：

10.3171/2012.5.PEDS11270

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors report on a case of histiocytic sarcoma (HS) in a pediatric patient presenting with a solitary tumor in the cerebellum, with the aim of providing insight into primary HS in the CNS, which is especially rare. A 17-month-old Japanese girl presented with a 2-week history of progressive gait disturbance. Brain MRI revealed a 4.7 x 4.3 x 4.3 cm well-demarcated solitary mass in the right hemisphere of the cerebellum, initially suggestive of medulloblastoma, ependymoma, or anaplastic astrocytoma. On intraoperative inspection the cerebellar tumor showed intensive dural attachment and was subtotally removed. Histological and immunohistochemical findings were consistent with HS. The patient subsequently received chemotherapy, and her preoperative neurological symptoms improved. Primary HS in the CNS usually demonstrates an aggressive clinical course and is currently considered to have a poor prognosis. The possibility of this rare tumor should be included in the differential diagnosis of localized cerebellar tumors in the pediatric age group. (http://thejns.org/doi/abs/10.3171/2012.5.PEDS11270)

引用

页码：126 / 129

页数：4