Enterotoxigenic and nontoxigenic Bacteroides fragilis strains isolated in Brazil

被引：3
作者：
Miranda, Karla R. [1 ]
Dias, Mariana F. [1 ]
Guimaraes, Priscilla L. S. [1 ]
Boente, Renata F. [1 ]
Pauer, Heidi [1 ]
Ramos, Priscila Z. [1 ]
Falcao, Lais S. [1 ]
Ferreira, Eliane de O. [1 ]
Balassiano, Ilana T. [2 ]
Ferreira, Livia Q. [1 ]
dos Santos-Filho, Joaquim [1 ]
de Paula, Geraldo R. [3 ]
Antunes, Eduardo N. F. [2 ]
Avelar, Katia E. S. [2 ]
Domingues, Regina M. C. P. [1 ]
机构：
[1] Univ Fed Rio de Janeiro, Inst Microbiol Prof Paulo Goes, Dept Med Microbiol, Lab Biol Anaerobios, BR-21941900 Rio De Janeiro, Brazil
[2] Inst Oswaldo Cruz Fiocruz, Lab Zoonoses Bacterianas, Rio De Janeiro, Brazil
[3] Univ Fed Fluminense, Fac Farm, Dept Tecnol Farmaceut, Niteroi, RJ, Brazil
来源：
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2008年 / 103卷 / 07期
关键词：
Bacteroides fragilis toxin; enterotoxigenic Bacteroides fragilis; nontoxigenic Bacteroides fragilis;
D O I：
10.1590/S0074-02762008000700018
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The presence of enterotoxigenic Bacteroides fragilis and nontoxigenic B. fragilis (NTBF) among 109 strains isolated from 1980-2008 in Brazil were investigated by PCR. One strain, representing 0.9% of the total analyzed strains, harbored the bft gene which was identified as bft-1 isoform based on PCR-RFLP and sequencing. Forty-nine strains (44.9%) exhibited the NTBF pattern III which possesses the flanking region required for pathogenicity island acquisition in which the bft gene is codified. These data reinforce the potential of B. fragilis as an emerging enteropathogen in our country.
引用
收藏
页码：734 / 735
页数：2
相关论文
共 39 条
  • [21] Enterotoxigenic Bacteroides fragilis activates IL-8 expression through Stat3 in colorectal cancer cells
    Purcell, Rachel V.
    Permain, Jessica
    Keenan, Jacqueline I.
    GUT PATHOGENS, 2022, 14 (01)
  • [22] Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota
    Odamaki, Toshitaka
    Sugahara, Hirosuke
    Yonezawa, Sumiko
    Yaeshima, Tomoko
    Iwatsuki, Keiji
    Tanabe, Soichi
    Tominaga, Tomoya
    Togashi, Hideo
    Benno, Yoshimi
    Xiao, Jin-zhong
    ANAEROBE, 2012, 18 (01) : 14 - 18
  • [23] Promotion of Colitis in B Cell-Deficient C57BL/6 Mice Infected with Enterotoxigenic Bacteroides fragilis
    Jo, Minjeong
    Hwang, Soonjae
    Lee, Chang-Gun
    Hong, Ju-Eun
    Kang, Da-Hye
    Yoo, Sang-Hyeon
    Kim, Woo-Seung
    Yoo, Jung-Yoon
    Rhee, Ki-Jong
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (01)
  • [24] The Relationship of Enterotoxigenic Bacteroides fragilis and Fusobacterium nucleatum Intestinal Colonization with Colorectal Cancer: A Case-Control Study Performed with Colon Biopsies
    Bakar, Yesim Ozturk
    Demiryas, Suleyman
    Kilincarslan, Ayse Ceylan
    Demirci, Mehmet
    Kepil, Nuray
    Bakar, Murat Tugberk
    Taner, Zeynep
    Tokuc, Edip
    Ziyad, Muhuyedin Abdirahman
    Tasci, Ihsan
    Kocazeybek, Bekir Sami
    Tokman, Hrisi Bahar
    MIKROBIYOLOJI BULTENI, 2023, 57 (03): : 353 - 364
  • [25] Toxigenic and non-toxigenic patterns I, II and III and biofilm-forming ability in Bacteroides fragilis strains isolated from patients diagnosed with colorectal cancer
    Jasemi, Seyedesomaye
    Emaneini, Mohammad
    Fazeli, Mohammad Sadegh
    Ahmadinejad, Zahra
    Nomanpour, Bizhan
    Heravi, Fatemah Sadeghpour
    Sechi, Leonardo A.
    Feizabadi, Mohammad Mehdi
    GUT PATHOGENS, 2020, 12 (01)
  • [26] Fecal Enterotoxigenic Bacteroides fragilis-Peptostreptococcus stomatis-Parvimonas micra Biomarker for Noninvasive Diagnosis and Prognosis of Colorectal Laterally Spreading Tumor
    Shen, Xiaonan
    Li, Jialu
    Li, Jiaqi
    Zhang, Yao
    Li, Xiaobo
    Cui, Yun
    Gao, Qinyan
    Chen, Xiaoyu
    Chen, Yingxuan
    Fang, Jing-Yuan
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [27] The Bacteroides fragilis Toxin Gene Is Prevalent in the Colon Mucosa of Colorectal Cancer Patients
    Boleij, Annemarie
    Hechenbleikner, Elizabeth M.
    Goodwin, Andrew C.
    Badani, Ruchi
    Stein, Ellen M.
    Lazarev, Mark G.
    Ellis, Brandon
    Carroll, Karen C.
    Albesiano, Emilia
    Wick, Elizabeth C.
    Platz, Elizabeth A.
    Pardoll, Drew M.
    Sears, Cynthia L.
    CLINICAL INFECTIOUS DISEASES, 2015, 60 (02) : 208 - 215
  • [28] Bacteroides fragilis in saliva: investigating links with ulcerative colitis
    Zamani, Samin
    Besharat, Sima
    Behnampour, Nasser
    Behnam, Armina
    Asgari, Negar
    Mortazavi, Nazanin
    BRAZILIAN JOURNAL OF MICROBIOLOGY, 2024, 55 (04) : 3691 - 3698
  • [29] The Mechanism of Bacteroides fragilis Toxin Contributes to Colon Cancer Formation
    Cheng, Wai Teng
    Kantilal, Haresh Kumar
    Davamani, Fabian
    MALAYSIAN JOURNAL OF MEDICAL SCIENCES, 2020, 27 (04): : 9 - 21
  • [30] KRAS mutations promote the intratumoral colonization of enterotoxigenic bacteroides fragilis in colorectal cancer through the regulation of the miRNA3655/SURF6/IRF7/IFNβ axis
    Chen, Yizhen
    Liu, Shaolin
    Tan, Song
    Zheng, Yuanyuan
    Chen, Yifan
    Yang, Changshun
    Lin, Shengtao
    Mi, Yulong
    Li, Weihua
    GUT MICROBES, 2024, 16 (01)
1234