20S ways to apoptosis

被引：2
|
作者：
McConkey, David J. [1 ,2 ]
机构：
[1] MD Anderson Canc Ctr, Dept Urol, Houston, TX 77030 USA
[2] MD Anderson Canc Ctr, Dept Canc Biol, Houston, TX 77030 USA
来源：
NATURE CHEMICAL BIOLOGY | 2008年 / 4卷 / 09期
关键词：
D O I：
10.1038/nchembio0908-528
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Chemical inhibitors of the proteasome have received substantial attention owing to the success of bortezomib in the treatment of multiple myeloma. A recent whole-cell screen identified the proteasome inhibitor argyrin A and suggests a new role for p27(Kip-1) in regulating apoptosis.
引用
收藏
页码：528 / 529
页数：3
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