20S ways to apoptosis

被引:2
|
作者
McConkey, David J. [1 ,2 ]
机构
[1] MD Anderson Canc Ctr, Dept Urol, Houston, TX 77030 USA
[2] MD Anderson Canc Ctr, Dept Canc Biol, Houston, TX 77030 USA
关键词
D O I
10.1038/nchembio0908-528
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Chemical inhibitors of the proteasome have received substantial attention owing to the success of bortezomib in the treatment of multiple myeloma. A recent whole-cell screen identified the proteasome inhibitor argyrin A and suggests a new role for p27(Kip-1) in regulating apoptosis.
引用
收藏
页码:528 / 529
页数:3
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