共 50 条
20S ways to apoptosis
被引:2
|作者:
McConkey, David J.
[1
,2
]
机构:
[1] MD Anderson Canc Ctr, Dept Urol, Houston, TX 77030 USA
[2] MD Anderson Canc Ctr, Dept Canc Biol, Houston, TX 77030 USA
关键词:
D O I:
10.1038/nchembio0908-528
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Chemical inhibitors of the proteasome have received substantial attention owing to the success of bortezomib in the treatment of multiple myeloma. A recent whole-cell screen identified the proteasome inhibitor argyrin A and suggests a new role for p27(Kip-1) in regulating apoptosis.
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页码:528 / 529
页数:3
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