Influenza A(H3N2) virus variants and patient characteristics during a summer influenza epidemic in Taiwan, 2017

被引：14
作者：
Tsou, Tsung-Pei [1 ]
Su, Chia-Ping [2 ,3 ]
Huan, Wan-Ting [2 ]
Yang, Ji-Rong [4 ]
Liu, Ming-Tsan [4 ]
机构：
[1] Minist Hlth & Welf, Div Preparedness & Emerging Infect Dis, Ctr Dis Control, Taipei, Taiwan
[2] Minist Hlth & Welf, Off Prevent Med, Ctr Dis Control, Taipei, Taiwan
[3] Natl Taiwan Univ, Inst Epidemiol & Prevent Med, Coll Publ Hlth, Taipei, Taiwan
[4] Minist Hlth & Welf, Ctr Res Diagnost & Vaccine Dev, Ctr Dis Control, Taipei, Taiwan
来源：
EUROSURVEILLANCE | 2017年 / 22卷 / 50期
关键词：
SURVEILLANCE; SEASON; SUBSTITUTIONS;
D O I：
10.2807/1560-7917.ES.2017.22.50.17-00767
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We report a summer influenza epidemic caused by co-circulation of multiple influenza A(H3N2) variants in clade 3C.2a. Compared with other clades, a putative clade 3C.2a.3a was more commonly isolated from severely ill patients; 3C.2a.4 was more commonly isolated in outbreak cases. Time from vaccination to illness onset was significantly shorter in severely ill patients infected with clade 3C.2a.3; characteristics and outcomes of patients infected with different clades were similar. No resistance to antiviral medications was found.
引用
收藏
页码：2 / 7
页数：6
相关论文
共 11 条
[1]  
[Anonymous], 2017, EXP OP NEUR INH PREV
[2]   Genetic divergence of Influenza A(H3N2) amino acid substitutions mark the beginning of the 2016-2017 winter season in Israel [J].
Glatman-Freedman, Aharona ;
Drori, Yaron ;
Beni, Sharon Alexandra ;
Friedman, Nehemya ;
Pando, Rakefet ;
Sefty, Hanna ;
Tal, Ilana ;
McCauley, John ;
Rahav, Galia ;
Keller, Nathan ;
Shohat, Tamy ;
Mendelson, Ella ;
Hindiyeh, Musa ;
Mandelboim, Michal .
JOURNAL OF CLINICAL VIROLOGY, 2017, 93 :71-75
[3]   Emergence of a novel subclade of influenza A(H3N2) virus in London, December 2016 to January 2017 [J].
Harvala, H. ;
Frampton, D. ;
Grant, P. ;
Raffle, J. ;
Ferns, R. B. ;
Kozlakidis, Z. ;
Kellam, P. ;
Pillay, D. ;
Hayward, A. ;
Nastouli, E. .
EUROSURVEILLANCE, 2017, 22 (08) :7-12
[4]   Mid-season real-time estimates of seasonal influenza vaccine effectiveness in persons 65 years and older in register-based surveillance, Stockholm County, Sweden, and Finland, January 2017 [J].
Hergens, M. ;
Baum, U. ;
Brytting, M. ;
Ikonen, N. ;
Haveri, A. ;
Wiman, A. ;
Nohynek, H. ;
Ortqvist, A. .
EUROSURVEILLANCE, 2017, 22 (08) :32-42
[5]   REAL-TIME SURVEILLANCE OF INFECTIOUS DISEASES: TAIWAN'S EXPERIENCE [J].
Jian, Shu-Wan ;
Chen, Chiu-Mei ;
Lee, Cheng-Yi ;
Liu, Ding-Ping .
HEALTH SECURITY, 2017, 15 (02) :144-153
[6]   Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution [J].
Koel, Bjorn F. ;
Burke, David F. ;
Bestebroer, Theo M. ;
van der Vliet, Stefan ;
Zondag, Gerben C. M. ;
Vervaet, Gaby ;
Skepner, Eugene ;
Lewis, Nicola S. ;
Spronken, Monique I. J. ;
Russell, Colin A. ;
Eropkin, Mikhail Y. ;
Hurt, Aeron C. ;
Barr, Ian G. ;
de Jong, Jan C. ;
Rimmelzwaan, Guus F. ;
Osterhaus, Albert D. M. E. ;
Fouchier, Ron A. M. ;
Smith, Derek J. .
SCIENCE, 2013, 342 (6161) :976-979
[7]   Predominance of influenza A(H3N2) virus genetic subclade 3C.2a1 during an early 2016/17 influenza season in Europe - Contribution of surveillance data from World Health Organization (WHO) European Region to the WHO vaccine composition consultation for northern hemisphere 2017/18 [J].
Melidou, Angeliki ;
Broberg, Eeva .
VACCINE, 2017, 35 (37) :4828-4835
[8]  
Rondy M, 2017, EURO SURVEILL, V22
[9]  
Skowronski DM, 2017, EUROSURVEILLANCE, V22, P2, DOI [10.2807/1560-7917.es.2017.22.6.30460, 10.2807/1560-7917.ES.2017.22.6.30460]
[10]   Changes in genetically drifted H3N2 influenza A viruses and vaccine effectiveness in adults 65 years and older during the 2016/17 season in Denmark [J].
Trebbien, Ramona ;
Fischer, Thea K. ;
Krause, Tyra G. ;
Nielsen, Lene ;
Nielsen, Xiaohui Chen ;
Weinreich, Lenette Sandborg ;
Lis-Tonder, Joanna ;
Skov, Marianne Nielsine ;
Christiansen, Claus Bohn ;
Emborg, Hanne-Dorthe .
JOURNAL OF CLINICAL VIROLOGY, 2017, 94 :1-7
12