Drug-induced Acute Liver Failure

被引：191

作者：

Lee, William M. ^{[1
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, Div Digest & Liver Dis, Dallas, TX 75390 USA

来源：

CLINICS IN LIVER DISEASE | 2013年 / 17卷 / 04期

关键词：

Hepatocyte injury; Encephalopathy; Coagulopathy; Liver transplantation; INTRAVENOUS N-ACETYLCYSTEINE; UNITED-STATES; INJURY; HEPATOTOXICITY; HEPATITIS; OUTCOMES; HYPERAMMONEMIA; MECHANISMS; PROGNOSIS; INFECTION;

D O I：

10.1016/j.cld.2013.07.001

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Although acute liver failure caused by drug-induced liver injury comprises a small fraction of overall drug-induced liver injury, these patients require high resource use and have relatively poor outcomes. Drug-induced liver injury caused by idiosyncrasy more often leads to death or transplantation than does acetaminophen acute liver failure, but the number of patients in each category receiving a graft is roughly the same. Efforts in the future to improve outcomes should focus on more effective treatments and better methods to identify those that might experience poor outcomes.

引用

页码：575 / +

页数：13

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