Thromboembolic complications in adult congenital heart disease: the knowns and the unknowns

被引：11

作者：

Karsenty, Clement ^{[1
,2
]}

Waldmann, Victor ^{[3
,4
,5
]}

Mulder, Barbara ^{[6
]}

Hascoet, Sebastien ^{[7
]}

Ladouceur, Magalie ^{[5
,8
]}

机构：

[1] Univ Toulouse, CHU Toulouse, Pediat & Congenital Cardiol, 330 Ave Grande Bretagne, F-31300 Toulouse, France

[2] Univ Toulouse, Inst Malad Metab & Cardiovasc, I2MC, INSERM U1048, 1 Ave Jean Poulhes BP84225, Toulouse, France

[3] Paris Descartes Univ, European Georges Pompidou Hosp, AP HP, Electrophysiol Unit,Dept Cardiol, Paris, France

[4] Paris Descartes Univ, European Georges Pompidou Hosp, AP HP, Adult Congenital Heart Dis Unit,Dept Cardiol, Paris, France

[5] Ctr Rech Cardiovasc Paris, INSERM U970, Paris, France

[6] Univ Amsterdam, Dept Cardiol, Locat AMC, Med Ctr, NL-1105 AZ Amsterdam, Netherlands

[7] Paris Sud Univ, Marie Lannelongue Hosp,Inserm U999, Ctr Reference Malformat Cardiaques Congenitales C, Dept Congenital Heart Dis,Grp Hosp Paris St Josep, Orsay, France

[8] Paris Descartes Univ, Hop Europeen Georges Pompidou, AP HP,M3C,Adult Congenital Heart Dis Unit, Ctr Reference Malformat Cardiaques Congenitales C, Paris, France

来源：

CLINICAL RESEARCH IN CARDIOLOGY | 2021年 / 110卷 / 09期

关键词：

Congenital heart disease; Thromboembolic events; Stroke; Management; PEDIATRIC CARDIAC-SURGERY; ATRIAL SEPTAL-DEFECT; INFECTIVE ENDOCARDITIS; FONTAN PROCEDURES; FOLLOW-UP; VENOUS THROMBOEMBOLISM; EMBOLIC COMPLICATIONS; PULMONARY THROMBOSIS; EISENMENGER SYNDROME; FACTOR ABNORMALITIES;

D O I：

10.1007/s00392-020-01746-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Despite impressive improvement in long-term survival, adults with congenital heart disease (CHD) remain exposed to a significant cardiovascular morbidity over lifetime. Thromboembolic events (TE) are a major issue. Specific anatomic groups have been shown a particular high risk of TE, including cyanotic heart disease and Fontan circulation. Many intercurrent clinical factors add a substantial risk such as intracardiac medical devices, atrial arrhythmia, endocarditis, or pregnancy. Nevertheless, what is unknown exceeds what is known, especially regarding the management of this heterogenous patient population. Anticoagulation decision should always be individualized weighing balanced with the alternative risk of hemorrhagic complications. In this review, we aim to synthetize existing literature on TE in adults with CHD, discuss management issues, highlight gaps in knowledge, and intend to suggest high priority research.

引用

页码：1380 / 1391

页数：12

共 100 条

[91] Risk of embolism and death in infective endocarditis: Prognostic value of echocardiography - A prospective multicenter study [J].

Thuny, F ;

Disalvo, G ;

Belliard, O ;

Avierinos, JF ;

Pergola, V ;

Rosenberg, V ;

Casalta, JP ;

Gouvernet, J ;

Derumeaux, G ;

Iarussi, D ;

Ambrosi, P ;

Calabro, R ;

Riberi, A ;

Collart, F ;

Metras, D ;

Lepidi, H ;

Raoult, D ;

Harle, JR ;

Weiller, PJ ;

Cohen, A ;

Habib, G .

CIRCULATION, 2005, 112 (01) :69-75

[92] Venous thromboembolism during pregnancy [J].

Toglia, MR ;

Weg, JG .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (02) :108-114

[93] Coagulation profile, hepatic function, and hemodynamics following Fontan-type operations [J].

Tomita, H ;

Yamada, O ;

Ohuchi, H ;

Ono, Y ;

Arakaki, Y ;

Yagihara, T ;

Echigo, S .

CARDIOLOGY IN THE YOUNG, 2001, 11 (01) :62-66

[94] Abnormalities in blood coagulation, fibrinolysis, and platelet activation in adult patients after the Fontan procedure [J].

Tomkiewicz-Pajak, Lidia ;

Hoffman, Piotr ;

Trojnarska, Olga ;

Lipczynska, Magdalena ;

Podolec, Piotr ;

Undas, Anetta .

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2014, 147 (04) :1284-1290

[95] Twenty-Five Year Experience With the St. Jude Medical Mechanical Valve Prosthesis [J].

Toole, J. Matthew ;

Stroud, Martha R. ;

Kratz, John M. ;

Crumbley, Arthur J., III ;

Bradley, Scott M. ;

Crawford, Fred A., Jr. ;

Ikonomidis, John S. .

ANNALS OF THORACIC SURGERY, 2010, 89 (05) :1402-1409

[96] Risk of surgery for congenital heart disease in the adult: A multicentered European study [J].

Vida, Vladimiro L. ;

Berggren, Hakan ;

Brawn, William J. ;

Daenen, Willem ;

Di Carlo, Duccio ;

Di Donato, Roberto ;

Lindberg, Harald L. ;

Corno, Antonio F. ;

Fragata, Jose ;

Elliott, Martin J. ;

Hraska, Viktor ;

Kiraly, Lazlo ;

Lacour-Gayet, Francois ;

Maruszewski, Bohdan ;

Rubay, Jean ;

Sairanen, Heikki ;

Sarris, George ;

Urban, Andreas ;

Van Doorn, Carin ;

Ziemer, Gerhard ;

Stellin, Giovanni .

ANNALS OF THORACIC SURGERY, 2007, 83 (01) :161-168

[97] THE EISENMENGER SYNDROME OR PULMONARY HYPERTENSION WITH REVERSED CENTRAL SHUNT [J].

WOOD, P .

BRITISH MEDICAL JOURNAL, 1958, 2 (SEP27) :755-762

[98] Non-vitamin K antagonist oral anticoagulants (NOACs) for thromboembolic prevention, are they safe in congenital heart disease? Results of a worldwide study [J].

Yang, H. ;

Bouma, B. J. ;

Dimopoulos, K. ;

Khairy, P. ;

Ladouceur, M. ;

Niwa, K. ;

Greutmann, M. ;

Schwerzmann, M. ;

Egbe, A. ;

Scognamiglio, G. ;

Budts, W. ;

Veldtman, G. ;

Opotowsky, A. R. ;

Broberg, C. S. ;

Gumbiene, L. ;

Meijboom, F. J. ;

Rutz, T. ;

Post, M. C. ;

Moe, T. ;

Lipczynska, M. ;

Tsai, S. F. ;

Chakrabarti, S. ;

Tobler, D. ;

Davidson, W. ;

Morissens, M. ;

van Dijk, A. ;

Buber, J. ;

Bouchardy, J. ;

Skoglund, K. ;

Christersson, C. ;

Kronvall, T. ;

Konings, T. C. ;

Alonso-Gonzalez, R. ;

Mizuno, A. ;

Webb, G. ;

Laukyte, M. ;

Sieswerda, G. T. J. ;

Shafer, K. ;

Aboulhosn, J. ;

Mulder, B. J. M. .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2020, 299 :123-130

[99] Non-vitamin K antagonist oral anticoagulants in adults with a Fontan circulation: are they safe [J].

Yang, Hayang ;

Veldtman, Gruschen R. ;

Bouma, Berto J. ;

Budts, Werner ;

Niwa, Koichiro ;

Meijboom, Folkert ;

Scognamiglio, Giancarlo ;

Egbe, Alexander Chima ;

Schwerzmann, Markus ;

Broberg, Craig ;

Morissens, Marielle ;

Buber, Jonathan ;

Tsai, Shane ;

Polyzois, Ioannis ;

Post, Martijn C. ;

Greutmann, Matthias ;

Van Dijk, Arie ;

Mulder, Barbara J. M. ;

Aboulhosn, Jamil .

OPEN HEART, 2019, 6 (01)

[100] Risk factors for in-hospital mortality during infective endocarditis in patients with congenital heart disease [J].

Yoshinaga, Masao ;

Niwa, Koichiro ;

Niwa, Atsuko ;

Ishiwada, Naruhiko ;

Takahashi, Hideto ;

Echigo, Shigeyuki ;

Nakazawa, Makoto .

AMERICAN JOURNAL OF CARDIOLOGY, 2008, 101 (01) :114-118

← 1 2 3 4 5 6 7 8 9 10 →