Innovative macromolecular syntheses via isocyanide multicomponent reactions

被引：80

作者：

Rudick, Jonathan G. ^{[1
]}

机构：

[1] SUNY Stony Brook, Dept Chem, Stony Brook, NY 11794 USA

来源：

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY | 2013年 / 51卷 / 19期

关键词：

block polymers; dendrimers; multicomponent reactions; polycondensation; star polymers; 3-COMPONENT COUPLING POLYMERIZATION; ALKYLENE BIS(TRIMETHYLSILYL) ETHERS; LIVING RADICAL POLYMERIZATION; PI-ALLYLPALLADIUM COMPLEX; SIMULTANEOUS CONSTRUCTION; SIDE-CHAINS; UGI REACTION; DENDRITIC MACROMOLECULES; POLYSACCHARIDE HYDROGELS; NMR CHARACTERIZATION;

D O I：

10.1002/pola.26808

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Isocyanide multicomponent reactions assemble more than two reaction components by exploiting the reactivity of the isocyanide carbon atom toward addition of electrophiles and nucleophiles. Reactions such as the Passerini three-component and Ugi four-component coupling reactions have a long and successful history in organic synthesis, which has only recently been explored in polymer chemistry. In a short time, this class of multicomponent reactions has been established as a viable method for the synthesis of linear polymers as well as more complex architectures such as miktoarm star polymers and dendrimers. This highlight discusses the recent accomplishments made with regard to innovative syntheses of polymers and dendrimers via the Passerini and Ugi reactions. (c) 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2013, 51, 3985-3991

引用

页码：3985 / 3991

页数：7

共 82 条

[11] Hyaluronan networking via Ugi's condensation using lysine as cross-linker diamine [J].

Crescenzi, V ;

Francescangeli, A ;

Capitani, D ;

Mannina, L ;

Renier, D ;

Bellini, D .

CARBOHYDRATE POLYMERS, 2003, 53 (03) :311-316

[12] Versatile synthesis of polysaccharide hydrogels using the Passerini and Ugi multicomponent condensations [J].

de Nooy, AEJ ;

Masci, G ;

Crescenzi, V .

MACROMOLECULES, 1999, 32 (04) :1318-1320

[13] Ionic polysaccharide hydrogels via the passerini and ugi multicomponent condensations: Synthesis, behavior and solid-state NMR characterization [J].

de Nooy, AEJ ;

Capitani, D ;

Masci, G ;

Crescenzi, V .

BIOMACROMOLECULES, 2000, 1 (02) :259-267

[14] Sequence Regulated Poly(ester-amide)s Based on Passerini Reaction [J].

Deng, Xin-Xing ;

Li, Lei ;

Li, Zi-Long ;

Lv, An ;

Du, Fu-Sheng ;

Li, Zi-Chen .

ACS MACRO LETTERS, 2012, 1 (11) :1300-1303

[15] Synthesis and NMR characterization of new hyaluronan-based NO donors [J].

Di Meo, C ;

Capitani, D ;

Mannina, L ;

Brancaleoni, E ;

Galesso, D ;

De Luca, G ;

Crescenzi, V .

BIOMACROMOLECULES, 2006, 7 (04) :1253-1260

[16] THE 7-COMPONENT REACTION [J].

DOMLING, A ;

UGI, I .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1993, 32 (04) :563-564

[17]

Dömling A, 2000, ANGEW CHEM INT EDIT, V39, P3168, DOI 10.1002/1521-3773(20000915)39:18<3168::AID-ANIE3168>3.0.CO

[18]

2-U

[19] Chemistry and Biology Of Multicomponent Reactions [J].

Domling, Alexander ;

Wang, Wei ;

Wang, Kan .

CHEMICAL REVIEWS, 2012, 112 (06) :3083-3135

[20] Chemotherapeutic Evaluation of a Synthetic Tubulysin Analogue-Dendrimer Conjugate in C26 Tumor Bearing Mice [J].

Floyd, William C., III ;

Datta, Gopal K. ;

Imamura, Shinichi ;

Kieler-Ferguson, Heidi M. ;

Jerger, Katherine ;

Patterson, Andrew W. ;

Fox, Megan E. ;

Szoka, Francis C. ;

Frechet, Jean M. J. ;

Ellman, Jonathan A. .

CHEMMEDCHEM, 2011, 6 (01) :49-53

← 1 2 3 4 5 6 7 8 9 →