With the purpose of studying the influence of Nd on the alloy structure and castability of ZM6, under the fixed content of Zn and Zr, this paper observes and analyzes the microstructure morphology of ZM6 alloy fracture with different Nd content by the means of uniaxial tension experiment and scanning electron microscope (SEM) observation. The search results indicate that the structure of ZM6 alloy after added Nd can be refined to some extent, while it has no obvious influence on the grain structure and dimension of as-ast ZM6 alloy. Through increasing the ratio between Nd and Zn, it turns out that Nd and Zn reduces their own solid solubility by each other in alpha-Mg, and meanwhile, they gather toward the grain boundary, which is beneficial to refine the structure of ZM6 alloy ingot and enables the grain dimension of ZM6 alloy to reach the minimum when the Nd content is 2.5 %. On the basis of the minimization of the grain dimension, the tensile property of ZM6 alloy improves with the Nd content. Thus, it provides theoretical guidance and technical support for the improvement of ZM6 alloy structure.