Optical Properties and In Vitro Biological Studies of Oligonucleotide-Modified Quantum Dots

被引：4

作者：

Gerard, Valerie A. ^{[1
,2
]}

Freeley, Mark ^{[1
,2
]}

Defrancq, Eric ^{[3
]}

Fedorov, Anatoly V. ^{[4
]}

Gun'ko, Yurii K. ^{[1
,2
,4
]}

机构：

[1] Trinity Coll Dublin, Sch Chem, Dublin 2, Ireland

[2] Trinity Coll Dublin, CRANN, Dublin 2, Ireland

[3] Univ Grenoble Alpes, Dept Chim Mol, UMR CNRS 5250, F-38000 Grenoble, France

[4] St Petersburg Natl Res Univ Informat Technol Mech, St Petersburg 197101, Russia

来源：

JOURNAL OF NANOMATERIALS | 2013年 / 2013卷

基金：

爱尔兰科学基金会;

关键词：

RESONANCE ENERGY-TRANSFER; NANOPARTICLES; CYTOTOXICITY; NANOCRYSTALS;

D O I：

10.1155/2013/463951

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Water-soluble semiconducting nanocrystals or quantum dots (QDs) have attracted much interest in recent years due to their tuneable emission and potential applications in photonics and biological imaging. Fluorescence resonance energy transfer (FRET) processes are very important for elucidating biochemical mechanisms in vitro, and QDs constitute an excellent substrate for this purpose. In this work, new oligonucleotide-functionalised CdTe-based QDs were prepared, characterised and biologically tested. These QDs demonstrated interesting optical properties as well as remarkable in vitro behaviour and potential for a range of biological applications.

引用

页数：10

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