Dasatinib promotes apoptosis of cutaneous squamous carcinoma cells by regulating activation of ERK1/2

被引:22
作者
Farshchian, Mehdi [1 ,2 ,3 ]
Nissinen, Liisa [1 ,2 ,3 ]
Grenman, Reidar [2 ,4 ]
Kahari, Veli-Matti [1 ,2 ,3 ]
机构
[1] Univ Turku, Dept Dermatol, POB 52, FI-20521 Turku, Finland
[2] Turku Univ Hosp, POB 52, FI-20521 Turku, Finland
[3] Univ Turku, MediCity Res Lab, Turku, Finland
[4] Univ Turku, Dept Otorhinolaryngol Head & Neck Surg, Turku, Finland
关键词
IMATINIB; CANCER; SKIN;
D O I
10.1111/exd.13109
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:89 / 92
页数:4
相关论文
共 9 条
[1]   Inhibition of Src Family Kinases and Receptor Tyrosine Kinases by Dasatinib: Possible Combinations in Solid Tumors [J].
Carlos Montero, Juan ;
Seoane, Samuel ;
Ocana, Alberto ;
Pandiella, Atanasio .
CLINICAL CANCER RESEARCH, 2011, 17 (17) :5546-5552
[2]   Treatment of Unresectable and Metastatic Cutaneous Squamous Cell Carcinoma [J].
Cranmer, Lee D. ;
Engelhardt, Candace ;
Morgan, Sherif S. .
ONCOLOGIST, 2010, 15 (12) :1320-1328
[3]   Imatinib in the treatment of solid tumours [J].
Duffaud, Florence ;
Le Cesne, Axel .
TARGETED ONCOLOGY, 2009, 4 (01) :45-56
[4]   EphB2 Promotes Progression of Cutaneous Squamous Cell Carcinoma [J].
Farshchian, Mehdi ;
Nissinen, Liisa ;
Siljamaki, Elina ;
Riihila, Pilvi ;
Toriseva, Mervi ;
Kivisaari, Atte ;
Ala-aho, Risto ;
Kallajoki, Markku ;
Verajankorva, Esko ;
Honkanen, Hanne-Kaisa ;
Heljasvaara, Ritva ;
Pihlajaniemi, Taina ;
Grenman, Reidar ;
Peltonen, Juha ;
Peltonen, Sirkku ;
Kahari, Veli-Matti .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 (07) :1882-1892
[5]   Eph receptors and ephrins in cancer: bidirectional signalling and beyond [J].
Pasquale, Elena B. .
NATURE REVIEWS CANCER, 2010, 10 (03) :165-180
[6]   Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib, reveal novel kinase and nonkinase targets [J].
Rix, Uwe ;
Hantschel, Oliver ;
Duernberger, Gerhard ;
Rix, Lily L. Remsing ;
Planyavsky, Melanie ;
Fernbach, Nora V. ;
Kaupe, Ines ;
Bennett, Keiryn L. ;
Valent, Peter ;
Colinge, Jacques ;
Kocher, Thomas ;
Superti-Furga, Giulio .
BLOOD, 2007, 110 (12) :4055-4063
[7]   Incidence Estimate of Nonmelanoma Skin Cancer in the United States, 2006 [J].
Rogers, Howard W. ;
Weinstock, Martin A. ;
Harris, Ashlynne R. ;
Hinckley, Michael R. ;
Feldman, Steven R. ;
Fleischer, Alan B. ;
Coldiron, Brett M. .
ARCHIVES OF DERMATOLOGY, 2010, 146 (03) :283-287
[8]   PROGNOSTIC FACTORS FOR LOCAL RECURRENCE, METASTASIS, AND SURVIVAL RATES IN SQUAMOUS-CELL CARCINOMA OF THE SKIN, EAR, AND LIP - IMPLICATIONS FOR TREATMENT MODALITY SELECTION [J].
ROWE, DE ;
CARROLL, RJ ;
DAY, CL .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1992, 26 (06) :976-990
[9]   Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias [J].
Talpaz, Moshe ;
Shah, Neil P. ;
Kantarjian, Hagop ;
Donato, Nicholas ;
Nicoll, John ;
Paquette, Ron ;
Cortes, Jorge ;
O'Brien, Susan ;
Nicaise, Claude ;
Bleickardt, Eric ;
Blackwood-Chirchir, M. Anne ;
Iyer, Vishwanath ;
Chen, Tai-Tsang ;
Huang, Fei ;
Decillis, Arthur P. ;
Sawyers, Charles L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (24) :2531-2541