Fatal cases of Chikungunya virus infection in Colombia: Diagnostic and treatment challenges

被引：41

作者：

de la Hoz, Juan M. ^{[1
,2
]}

Bayona, Brayan ^{[1
]}

Viloria, Samir ^{[3
]}

Accini, Jose L. ^{[4
]}

Juan-Vergara, Homero San ^{[1
]}

Viasus, Diego ^{[1
,2
]}

机构：

[1] Univ Norte, Div Hlth Sci, Barranquilla, Colombia

[2] Hosp Univ Norte, Dept Internal Med, Barranquilla, Colombia

[3] Hosp Univ Norte, Dept Microbiol, Barranquilla, Colombia

[4] Hosp Univ Norte, Intens Care Unit, Barranquilla, Colombia

来源：

JOURNAL OF CLINICAL VIROLOGY | 2015年 / 69卷

关键词：

Chikungunya; Dengue; Mortality; Clinical feature; Laboratory finding; GABON; FEVER;

D O I：

10.1016/j.jcv.2015.05.021

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Although Chikungunya infection is emerging as an important public health problem in many countries, it is not regarded as a life-threatening disease. Information dealing with fatal cases is scarce. We herein describe three patients with Chickungunya infection who presented with multiple organ failure and died within 24 h of admission. Two cases had positive anti-dengue IgM, but dengue coinfection was rejected based on the clinical features and results of real-time reverse transcription polymerase chain reaction. These cases illustrate the challenges of the diagnosis and management of severe Chikungunya infection. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：27 / 29

页数：3

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