Structural features underlying recognition and translocation of extracellular polysaccharides

被引:12
作者
Zimmer, Jochen [1 ]
机构
[1] Univ Virginia, 480 Ray C Hunt Dr, Charlottesville, VA 22903 USA
关键词
complex carbohydrate; membrane transport; polysaccharide; transporter; BACTERIAL CELLULOSE SYNTHASE; CAPSULAR POLYSACCHARIDES; BINDING MODULES; OUTER-MEMBRANE; PROTEIN; CELLOBIOHYDROLASE; BIOSYNTHESIS; MECHANISM; ARCHITECTURE; HYALURONAN;
D O I
10.1098/rsfs.2018.0060
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Essentially all living systems produce complex carbohydrates as an energy source, structural component, protective coat or adhesive for cell attachment. Many polysaccharides are displayed on the cell surface or are threaded through proteinaceous tunnels for degradation. Dictated by their chemical composition and mode of polymerization, the physical properties of complex carbohydrates differ substantially, from amphipathic water-insoluble polymers to highly hydrated hydrogel-forming macromolecules. Accordingly, diverse recognition and translocation mechanisms evolved to transport polysaccharides to their final destinations. This review will summarize and compare diverse polysaccharide transport mechanisms implicated in the biosynthesis and degradation of cell surface polymers in pro- and eukaryotes.
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页数:9
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