Transforming growth factor alpha-immunoreactivity in neural tissues of the rat stomach

被引：6
作者：
Hoffmann, P
Zeeh, JM
Lakshmanan, J
Liu, L
Cooray, D
Barajas, L
Eysselein, VE
机构：
[1] HARBOR UCLA MED CTR,DIV GASTROENTEROL,TORRANCE,CA 90509
[2] HARBOR UCLA MED CTR,DIV PATHOL,TORRANCE,CA 90509
来源：
REGULATORY PEPTIDES | 1997年 / 69卷 / 03期
关键词：
transforming growth factor alpha; epidermal growth factor; stomach; nerves; immunohistochemistry;
D O I：
10.1016/S0167-0115(97)02131-9
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report TGF alpha immunoreactivity in neurons of the myenteric plexus and in nerve fibers in the muscle and submucosal layers of the rat stomach. Association of TGF alpha staining nerve fibers to vessels and smooth muscle cells gives morphological evidence that EGF/TGF alpha's actions to increase mucosal blood flow and gastric motility may be mediated by TGF alpha derived from neural structures. These data suggest that TGF alpha plays a role in the neural control of the gastric function. (C) 1997 Elsevier Science B.V. All rights reserved.
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收藏
页码：121 / 125
页数：5
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