Conventional Biomarkers for Predicting Clinical Outcomes in Patients with Heart Disease

被引：3
作者：
Manescu, Ion-Bogdan [1 ,2 ]
Pal, Krisztina [1 ,2 ]
Lupu, Silvia [3 ,4 ]
Dobreanu, Minodora [1 ,2 ,5 ]
机构：
[1] Cty Emergency Clin Hosp Targu Mures, Clin Lab, Targu Mures 540136, Romania
[2] George Emil Palade Univ Med Pharm Sci & Technol T, Dept Lab Med, Targu Mures 540142, Romania
[3] George Emil Palade Univ Med Pharm Sci & Technol T, Internal Med 5, Targu Mures 540142, Romania
[4] Emergency Inst Cardiovasc Dis & Heart Transplant, Dept Cardiol 1, Targu Mures 540136, Romania
[5] George Emil Palade Univ Med Pharm Sci & Technol T, Ctr Adv Med & Pharmaceut Res, Targu Mures 540139, Romania
来源：
LIFE-BASEL | 2022年 / 12卷 / 12期
关键词：
coronary artery disease; acute coronary syndrome; heart failure; biomarkers; ACUTE CORONARY SYNDROME; ELEVATION MYOCARDIAL-INFARCTION; REDUCED EJECTION FRACTION; NATRIURETIC PEPTIDE; FAILURE HOSPITALIZATION; CARDIOVASCULAR OUTCOMES; TROPONIN-I; MORTALITY; RISK; ASSOCIATION;
D O I：
10.3390/life12122112
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Atherosclerosis is the main cause of cardiovascular disease worldwide. The progression of coronary atherosclerosis leads to coronary artery disease, with impaired blood flow to the myocardium and subsequent development of myocardial ischemia. Acute coronary syndromes and post-myocardial infarction heart failure are two of the most common complications of coronary artery disease and are associated with worse outcomes. In order to improve the management of patients with coronary artery disease and avoid major cardiovascular events, several risk assessment tools have been developed. Blood and imaging biomarkers, as well as clinical risk scores, are now available and validated for clinical practice, but research continues. The purpose of the current paper is to provide a review of recent findings regarding the use of humoral biomarkers for risk assessment in patients with heart disease.
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页数：17
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