Visuospatial and Attentional Abilities Predict Driving Simulator Performance Among Older HIV-infected Adults

被引：25
作者：
Foley, J. M. [1 ,2 ]
Gooding, A. L. [3 ]
Thames, A. D. [4 ]
Ettenhofer, M. L. [5 ]
Kim, M. S. [2 ,6 ]
Castellon, S. A. [4 ,7 ]
Marcotte, T. D. [8 ]
Sadek, J. R. [9 ]
Heaton, R. K. [8 ]
van Gorp, W. G. [10 ]
Hinkin, C. H. [4 ,7 ]
机构：
[1] VA Boston Healthcare Syst, Boston, MA 02130 USA
[2] Harvard Univ, Sch Med, Dept Psychiat, Boston, MA 02115 USA
[3] Fordham Univ, Dept Psychol, New York, NY 10023 USA
[4] Univ Calif Los Angeles, Semel Inst Neurosci & Human Behav, Los Angeles, CA USA
[5] Uniformed Serv Univ Hlth Sci, Bethesda, NE USA
[6] Cambridge Hlth Alliance, Cambridge, MA USA
[7] VA Med Ctr, Los Angeles, CA USA
[8] Univ Calif San Diego, Sch Med, Dept Psychiat, San Diego, CA 92103 USA
[9] Univ New Mexico, New Mexico VAMC, Dept Psychiat, Albuquerque, NM 87131 USA
[10] Columbia Presbyterian Med Ctr, New York, NY 10032 USA
来源：
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS | 2013年 / 28卷 / 02期
关键词：
HIV; aging; driving performance; independent functioning; cognition; HUMAN-IMMUNODEFICIENCY-VIRUS; VISUAL-ATTENTION; MEDICATION ADHERENCE; NEUROPSYCHOLOGICAL IMPAIRMENT; PARKINSONS-DISEASE; CAR CRASHES; DRIVERS; DEMENTIA; SAFETY; IMPACT;
D O I：
10.1177/1533317512473192
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Objectives: To examine the effects of aging and neuropsychological (NP) impairment on driving simulator performance within a human immunodeficiency virus (HIV)-infected cohort. Methods: Participants included 79 HIV-infected adults (n = 58 > age 50, n = 21 <= 40) who completed a NP battery and a personnel computer-based driving simulator task. Outcome variables included total completion time (time) and number of city blocks to complete the task (blocks). Results: Compared to the younger group, the older group was less efficient in their route finding (blocks over optimum: 25.9 [20.1] vs 14.4 [16.9]; P = .02) and took longer to complete the task (time: 1297.6 [577.6] vs 804.4 [458.5] seconds; P = .001). Regression models within the older adult group indicated that visuospatial abilities (blocks: b = -0.40, P < .001; time: b = -0.40, P = .001) and attention (blocks: b = -0.49, P = .001; time: b = -0.42, P = .006) independently predicted simulator performance. The NP-impaired group performed more poorly on both time and blocks, compared to the NP normal group. Conclusions: Older HIV-infected adults may be at risk of driving-related functional compromise secondary to HIV-associated neurocognitive decline.
引用
收藏
页码：185 / 194
页数：10
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