Functionalized Fe3O4 Nanoparticles for Detecting Zinc Ions in Living Cells and Their Cytotoxicity

被引：27

作者：

Kang, Gyusik ^{[2
,3
]}

Son, Hyunjong ^{[2
,3
]}

Lim, Jung Mi ^{[1
]}

Kweon, Hee-Seek ^{[4
]}

Lee, In Soo ^{[5
]}

Kang, Dongmin ^{[1
]}

Jung, Jong Hwa ^{[2
,3
]}

机构：

[1] Ewha Womans Univ, Div Life & Pharmaceut Sci, Seoul 120750, South Korea

[2] Gyeongsang Natl Univ, Dept Chem, Jinju 660701, South Korea

[3] Gyeongsang Natl Univ, Res Inst Nat Sci, Jinju 660701, South Korea

[4] Korea Basic Sci Inst, Div Electron Microscop Res, Taejon 305333, South Korea

[5] Pohang Univ Sci & Technol, Dept Chem, Pohang 790784, South Korea

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2012年 / 18卷 / 19期

关键词：

biosensors; chromophores; fluorophores; nanoparticles; zinc; SELECTIVE FLUORESCENT SENSOR; MAGNETIC NANOPARTICLES; AQUEOUS-MEDIA; PROBE; CHEMOSENSOR; ZN2+; LUMINESCENT; RECOGNITION; CADMIUM; ZN(II);

D O I：

10.1002/chem.201200294

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe 3O 4 nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn 2+ over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn 2+ levels in living cells (see figure). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：5843 / 5847

页数：5

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