Neuropathologic findings in essential tremor

被引：109
作者：
Louis, ED
Vonsattel, JPG
Honig, LS
Ross, GW
Lyons, KE
Pahwa, R
机构：
[1] Columbia Univ Coll Phys & Surg, GH Sergievsky Ctr, New York, NY 10032 USA
[2] Columbia Univ Coll Phys & Surg, Dept Neurol, New York, NY 10032 USA
[3] Columbia Univ Coll Phys & Surg, Taub Inst Res & Alzheimers Dis & Aging Brain, New York, NY 10032 USA
[4] Columbia Univ Coll Phys & Surg, Dept Pathol, New York, NY 10032 USA
[5] Vet Affairs Pacific Isl Hlth care Syst, Honolulu, HI USA
[6] Univ Hawaii, John A Burns Sch Med, Dept Med, Honolulu, HI 96822 USA
[7] Univ Hawaii, John A Burns Sch Med, Dept Geriatr, Honolulu, HI 96822 USA
[8] Kuakini Med Ctr, Honolulu Asia Aging Study, Pacific Hlth Res Inst, Honolulu, HI USA
[9] Univ Kansas, Med Ctr, Dept Neurol, Kansas City, KS USA
来源：
NEUROLOGY | 2006年 / 66卷 / 11期
关键词：
D O I：
10.1212/01.wnl.0000218162.80315.b9
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Pathologic findings, including cerebellar changes and brainstem Lewy bodies, distinguished 10 essential tremor (ET) cases from 12 controls. Numbers of torpedoes (p = 0.009) and Bergmann glia (p = 0.046) were increased in cases. Six cases (60%) had Lewy bodies vs 2 controls (16.7%) (odds ratio 7.5, 95% CI 1.04 to 54.1; p = 0.035). Four of these six had an atypical distribution of brainstem Lewy bodies. ET may be pathologically heterogeneous.
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收藏
页码：1756 / 1759
页数：4
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