New Metal-Free One-Pot Synthesis of Substituted Allenes from Enones

被引：27

作者：

Tang, Meng

Fan, Chun-An

Zhang, Fu-Min

Tu, Yong-Qiang ^{[1
]}

Zhang, Wen-Xue

Wang, Ai-Xia

机构：

[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 24期

关键词：

D O I：

10.1021/ol802445p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new metal-free, one-pot synthesis of substituted allenes from enones was discovered for the first time, in which a tertiary amine as a base was found to be an effective promoter in such novel transformations. The present synthetic protocol proceeded readily with high compatibility of sensitive functional groups, and it provides a new efficient way to access a series of synthetically important allenes without the use of metallic reagents or catalysts.

引用

页码：5585 / 5588

页数：4

共 59 条

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