Asymmetric synthesis of the Abbott amino dihydroxyethylene dipeptide isostere subunit

被引：11

作者：

Haddad, M

Larcheveque, M

机构：

[1] Lab. de Synt. Organique Associe, ENSCP, 75231 Paris Cedex 05

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 26期

关键词：

D O I：

10.1016/0040-4039(96)00874-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The aminodiol 1b, a N-benzyl protected form of the Abbott dipeptide isostere la is prepared, starling from an appropriate alpha,beta-unsaturated ester, involving an asymmetric dihydroxylation and a rearrangement of an intermediate anti alpha,beta-aminoepoxide. Copyright (C) 1996 Published by Elsevier Science Ltd

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页码：4525 / 4528

页数：4

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