Toward Quantitative Chemical Analysis Using a Ruler on Paper: An Approach to Transduce Color to Length Based on Coffee-Ring Effect

被引：45

作者：

Zhang, Dagan ^{[1
]}

Ma, Biao ^{[1
]}

Tang, Litianyi ^{[1
]}

Liu, Hong ^{[1
]}

机构：

[1] Southeast Univ, Sch Biol Sci & Med Engn, State Key Lab Bioelect, Nanjing 210096, Jiangsu, Peoples R China

来源：

ANALYTICAL CHEMISTRY | 2018年 / 90卷 / 03期

基金：

中国国家自然科学基金;

关键词：

COLORIMETRIC DETECTION; MICROFLUIDIC DEVICES; GOLD NANOPARTICLES; PHOTONIC CRYSTALS; SEPARATION; DIPSTICK; HYDROGEL; FLOW;

D O I：

10.1021/acs.analchem.7b03790

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We report a quantitative analytical method using the naked eye. The method is based on the coffee-ring effect on paper, which converts a colored solution to stains on the paper. It is found that the width of the colored stains is correlated to the concentration of analyte so that quantitative analysis can be accomplished using a ruler. The influence of the shape and lamination of the paper reservoir to the test results is studied to find the optimal one for unambiguous analysis. It is also found that the sample color does not cause interference to the test. The applicability of the method to quantitative chemical analysis is demonstrated by detection of glucose and lactate.

引用

页码：1482 / 1486

页数：5