Pharmacological Primary Prevention of Diabetes Mellitus Type II: A Narrative Review

被引:5
作者
Naveed, Ali [1 ,2 ]
Farrukh, Larabe [1 ,2 ]
Sana, Muhammad Khawar [1 ,2 ]
Naveed, Bazigh [1 ,2 ]
Randhawa, Fawad Ahmad [2 ,3 ]
机构
[1] King Edward Med Univ, Internal Med, Lahore, Pakistan
[2] Mayo Hosp, Lahore, Pakistan
[3] King Edward Med Univ, Diabet & Endocrinol, Lahore, Pakistan
关键词
primary prevention; pharmacological prevention; diabetes mellitus type ii; pre-diabetes; IMPAIRED GLUCOSE-TOLERANCE; LIFE-STYLE MODIFICATION; METABOLIC SYNDROME; FASTING GLUCOSE; HIGH-RISK; ACARBOSE; ROSIGLITAZONE; COMPLICATIONS; INDIVIDUALS; LIRAGLUTIDE;
D O I
10.7759/cureus.10033
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The evolving epidemic of type 2 diabetes mellitus has challenged health-care professionals. It stands among the leading causes of mortality in the present world. It warrants new and versatile approaches to improve mortality and the associated huge quality-adjusted life years lost to it once diagnosed. A possible venue to lower the incidence is to assess the safety and efficacy of various diabetes prevention strategies. Diet and exercise have a well-developed role in the prevention of weight gain and, ultimately, diabetes mellitus type II in high-risk individuals. However, high-risk individuals can also benefit from adjunct pharmacotherapy. In light of this information, we decided to conduct a systematic review of randomized controlled trials. This article summarizes the evidence in the literature on the pharmacological prevention of diabetes in high-risk individuals.
引用
收藏
页数:11
相关论文
共 40 条
[1]   Mechanism linking diabetes mellitus and obesity [J].
Al-Goblan, Abdullah S. ;
Al-Alfi, Mohammed A. ;
Khan, Muhammad Z. .
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2014, 7 :587-591
[2]   Effects of Different Dietary and Lifestyle Modification Therapies on Metabolic Syndrome in Prediabetic Arab Patients: A 12-Month Longitudinal Study [J].
Alfawaz, Hanan A. ;
Wani, Kaiser ;
Alnaami, Abdullah M. ;
Al-Saleh, Yousef ;
Aljohani, Naji J. ;
Al-Attas, Omar S. ;
Alokail, Majed S. ;
Kumar, Sudhesh ;
Al-Daghri, Nasser M. .
NUTRIENTS, 2018, 10 (03)
[3]   Effect of liraglutide administration and a calorie-restricted diet on lipoprotein profile in overweight/obese persons with prediabetes [J].
Ariel, D. ;
Kim, S. H. ;
Abbasi, F. ;
Lamendola, C. A. ;
Liu, A. ;
Reaven, G. M. .
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2014, 24 (12) :1317-1322
[4]   Preservation of pancreatic β-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk Hispanic women [J].
Buchanan, TA ;
Xiang, AH ;
Peters, RK ;
Kjos, SL ;
Marroquin, A ;
Goico, J ;
Ochoa, C ;
Tan, S ;
Berkowitz, K ;
Hodis, HN ;
Azen, SP .
DIABETES, 2002, 51 (09) :2796-2803
[5]  
Centers for Disease Control and Prevention, 2020, EST DIAB ITS BURD US
[6]   Determinants of Sedentary Behavior, Motivation, Barriers and Strategies to Reduce Sitting Time in Older Women: A Qualitative Investigation [J].
Chastin, Sebastien F. M. ;
Fitzpatrick, Nicole ;
Andrews, Michelle ;
DiCroce, Natalie .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2014, 11 (01) :773-791
[7]   Acarbose for prevention of type 2 diabetes mellitus: the STOPNIDDM randomised trial [J].
Chiasson, JL ;
Josse, RG ;
Gomis, R ;
Hanefeld, M ;
Karasik, A ;
Laakso, M .
LANCET, 2002, 359 (9323) :2072-2077
[8]  
Chong Shanley, 2017, Diabetes Spectr, V30, P43, DOI 10.2337/ds15-0044
[9]   Insulin action and resistance in obesity and type 2 diabetes [J].
Czech, Michael P. .
NATURE MEDICINE, 2017, 23 (07) :804-814
[10]   Thiazolidinedione therapy in the prevention/delay of type 2 diabetes in patients with impaired glucose tolerance and insulin resistance [J].
Durbin, RJ .
DIABETES OBESITY & METABOLISM, 2004, 6 (04) :280-285