Gold-mediated selective cysteine modification of peptides using allenes

被引：35
作者：
Chan, Anna On-Yee [1 ,2 ]
Tsai, Johnson Lui-Lui [1 ,2 ]
Lo, Vanessa Kar-Yan [1 ,2 ]
Li, Gai-Li [3 ]
Wong, Man-Kin [3 ]
Che, Chi-Ming [1 ,2 ]
机构：
[1] Univ Hong Kong, Dept Chem, State Key Lab Synthet Chem, Hong Kong, Hong Kong, Peoples R China
[2] Univ Hong Kong, Inst Mol Technol Drug Discovery & Synth, Open Lab Chem Biol, Hong Kong, Hong Kong, Peoples R China
[3] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 14期
关键词：
CONVERGENT CHEMICAL-SYNTHESIS; POSTTRANSLATIONAL MODIFICATIONS; HIGHLY EFFICIENT; AQUEOUS-MEDIUM; ALLYLIC SELENOSULFIDE; RHODIUM CARBENOIDS; AMIDE SYNTHESIS; PROTEINS; LIGATION; CHEMISTRY;
D O I：
10.1039/c2cc38214h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new approach for selective modification of cysteine-containing peptides through gold-mediated oxidative allene-thiol coupling reaction in aqueous medium is developed.
引用
收藏
页码：1428 / 1430
页数：3
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