Submillimeter-resolution magnetic resonance imaging at the Earth's magnetic field with an atomic magnetometer

被引:53
作者
Xu, Shoujun [2 ]
Crawford, C. W. [2 ]
Rochester, Simon [1 ]
Yashchuk, Valeriy
Budker, Dmitry [1 ]
Pines, Alexander [2 ]
机构
[1] Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
来源
PHYSICAL REVIEW A | 2008年 / 78卷 / 01期
关键词
D O I
10.1103/PhysRevA.78.013404
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Magnetic resonance imaging in the Earth's magnetic field is achieved using a sensitive atomic magnetometer for detection. We demonstrate images with a submillimeter resolution by recording the flow of two water paths meeting at a T-shaped mixer. The high homogeneity of the Earth's field allows the use of weak gradient fields which circumvent the concomitant-field effect. To distinguish the two input channels, we employed selective polarization, which is a unique and noninvasive labeling method for low-field magnetic resonance imaging. Our technique imposes minimal physical constraints on the object under study, in contrast to conventional high-field magnetic resonance imaging. This technique is applicable for microfluidic imaging in laboratory-on-a-chip devices.
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页数:4
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共 24 条
[1]   PARA-HYDROGEN AND SYNTHESIS ALLOW DRAMATICALLY ENHANCED NUCLEAR ALIGNMENT [J].
BOWERS, CR ;
WEITEKAMP, DP .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (18) :5541-5542
[2]   Resonant nonlinear magneto-optical effects in atoms [J].
Budker, D ;
Gawlik, W ;
Kimball, DF ;
Rochester, SM ;
Yashchuk, VV ;
Weis, A .
REVIEWS OF MODERN PHYSICS, 2002, 74 (04) :1153-1201
[3]   Optical magnetometry [J].
Budker, Dmitry ;
Romalis, Michael .
NATURE PHYSICS, 2007, 3 (04) :227-234
[4]   Single-molecule fluorescence detection in microfluidic channels -: the Holy Grail in μTAS? [J].
Dittrich, PS ;
Manz, A .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2005, 382 (08) :1771-1782
[5]   Nuclear magnetic resonance of laser-polarized noble gases in molecules, materials, and organisms [J].
Goodson, BM .
JOURNAL OF MAGNETIC RESONANCE, 2002, 155 (02) :157-216
[6]   A practical and flexible implementation of 3D MRI in the Earth's magnetic field [J].
Halse, Meghan E. ;
Coy, Andrew ;
Dykstra, Robin ;
Eccles, Craig ;
Hunter, Mark ;
Ward, Rob ;
Callaghan, Paul T. .
JOURNAL OF MAGNETIC RESONANCE, 2006, 182 (01) :75-83
[7]   Time-of-flight flow imaging of two-component flow inside a microfluidic chip [J].
Harel, Elad ;
Hilty, Christian ;
Koen, Katherine ;
McDonnell, Erin E. ;
Pines, Alex .
PHYSICAL REVIEW LETTERS, 2007, 98 (01)
[8]   Scaling and the design of miniaturized chemical-analysis systems [J].
Janasek, Dirk ;
Franzke, Joachim ;
Manz, Andreas .
NATURE, 2006, 442 (7101) :374-380
[9]   In situ temperature jump high-frequency dynamic nuclear polarization experiments: Enhanced sensitivity in liquid-state NMR spectroscopy [J].
Joo, Chan-Gyu ;
Hu, Kan-Nian ;
Bryant, Jeffrey A. ;
Griffin, Robert G. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (29) :9428-9432
[10]   Superconducting quantum interference devices: State of the art and application's [J].
Kleiner, R ;
Koelle, D ;
Ludwig, F ;
Clarke, J .
PROCEEDINGS OF THE IEEE, 2004, 92 (10) :1534-1548