Salivary duct carcinoma with striking neutrophil-tumor cell cannibalism

被引：14

作者：

Arya, Payam ^{[1
]}

Khalbuss, Walid E. ^{[1
]}

Monaco, Sara E. ^{[1
]}

Pantanowitz, Liron ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Pathol, Med Ctr, Pittsburgh, PA 15260 USA

来源：

CYTOJOURNAL | 2011年 / 8卷

关键词：

Cannibalism; duct carcinoma; neutrophils; phagocytosis; salivary gland; CANCER; PHAGOCYTOSIS; LUNG;

D O I：

10.4103/1742-6413.84222

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Cannibalism of neutrophils by tumor cells has previously been reported in certain carcinomas, lymphoma and melanoma. Tumor cannibalism is believed to serve as a tumor-immune escape mechanism, associated with high-grade aggressive cancers with a significantly increased metastatic potential. This interesting phenomenon has not been previously documented in association with salivary gland tumors. We report, for the first time, striking neutrophil-tumor cell cannibalism associated with a high grade, aggressive and metastatic salivary duct carcinoma of the parotid gland highlighted within cytological and surgical excision pathology specimens.

引用

页数：4

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