News on Infantile Hemangioma Therapy by Beta-blocker

被引:0
作者
Delmotte, Nicolas
Curti, Christophe [1 ,2 ]
Montana, Marc [1 ,3 ]
Crozet, Maxime [1 ]
Vanelle, Patrice [1 ,2 ]
Gensollen, Sophie
机构
[1] CNRS, UMR 6264, Fac Pharm Timone, Lab Pharmacochim Radicalaire, F-13385 Marseille 05, France
[2] Hop Conception, AP HM, Serv Cent Qual & Informat Pharmaceut, Marseille, France
[3] Hop Nord Marseille, AP HM, Marseille, France
来源
THERAPIE | 2012年 / 67卷 / 03期
关键词
hemangioma; beta blockers; propranolol; neonate; PROPRANOLOL; HYPOGLYCEMIA; STRATEGY;
D O I
10.2515/therapie/2012033
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
News on Infantile Hemangioma Therapy by Beta-blocker. Hemangiomas are benign tumors most commonly encountered in infancy and early childhood. While most of them regress spontaneously, some require treatment due to a significant proliferation, which may be complicated by ulceration, deformation aesthetic deformation or worse impairment vital. Among the treatments used corticosteroids is the standard treatment but its use in high doses expose to potential risks. In 2008, the discovery by "chance" of the effectiveness of propranolol in the management of hemangioma revolutionizes the first line treatment. Its mechanism of action is not yet well understood and establishment of such treatment should be done by a hospital paediatrician in the absence of any contraindications. This article proposes focus on effectiveness and tolerance of beta-blockers used as treatment of infantile hemangiomas.
引用
收藏
页码:257 / 265
页数:9
相关论文
共 47 条
  • [1] Albanese J, 2005, PRINCIPE REANIMATION, P64
  • [2] [Anonymous], GOODMAN GILMANS PHAR
  • [3] [Anonymous], 2010, PIERR FABR DERM PUT
  • [4] Evaluation of intralesional propranolol for periocular capillary hemangioma
    Awadein, Ahmed
    Fakhry, Mohamed A.
    [J]. CLINICAL OPHTHALMOLOGY, 2011, 5 : 1135 - 1140
  • [5] Propranolol for Infantile Hemangiomas
    Bagazgoitia, Lorea
    Torrelo, Antonio
    Lopez Gutierrez, Juan Carlos
    Hernandez-Martin, Angela
    Luna, Paula
    Gutierrez, Marta
    Bano, Antonio
    Tamariz, Amalia
    Larralde, Margarita
    Alvarez, Roser
    Pardo, Nuria
    Baselga, Eulalia
    [J]. PEDIATRIC DERMATOLOGY, 2011, 28 (02) : 108 - 114
  • [6] Bigorre M, 2009, J PLAST RECONSTR AES, V123, P195
  • [7] Hypoglycemia as a Result of Propranolol During Treatment of Infantile Hemangioma: A Case Report
    Breur, Johannes M. P. J.
    de Graaf, Marlies
    Breugem, Corstiaan C.
    Pasmans, Suzanne G. M. A.
    [J]. PEDIATRIC DERMATOLOGY, 2011, 28 (02) : 169 - 171
  • [8] Placental hypoxia and neonatal haemangioma: clinical and histological observations
    Colonna, V.
    Resta, L.
    Napoli, A.
    Bonifazi, E.
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2010, 162 (01) : 208 - 209
  • [9] Adverse effects of propranolol when used in the treatment of hemangiomas: A case series of 28 infants
    de Graaf, Marlies
    Breur, Johannes M. P. J.
    Raphael, Martine F.
    Vos, Marike
    Breugem, Corstiaan C.
    Pasmans, Suzanne G. M. A.
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2011, 65 (02) : 320 - 327
  • [10] Role of Propranolol in the therapeutic strategy of infantile laryngotracheal hemangioma
    Denoyelle, Francoise
    Leboulanger, Nicolas
    Enjolras, Odile
    Harris, Robert
    Roger, Gilles
    Garabedian, Erea-Noel
    [J]. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2009, 73 (08) : 1168 - 1172