The calcium-ROS-pH triangle and mitochondrial permeability transition: challenges to mimic cardiac ischemia-reperfusion

被引：10
作者：
Javadov, Sabzali [1 ]
机构：
[1] Univ Puerto Rico, Sch Med, Dept Physiol, San Juan, PR 00936 USA
来源：
FRONTIERS IN PHYSIOLOGY | 2015年 / 6卷
关键词：
cardiac ischemia-reperfusion; mitochondria; permeability transition pore; calcium; ROS; pH; ATP SYNTHASE; PORE; INHIBITION; CHANNEL;
D O I：
10.3389/fphys.2015.00083
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
引用
收藏
页数：3
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  • [1] An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore
    Alavian, Kambiz N.
    Beutner, Gisela
    Lazrove, Emma
    Sacchetti, Silvio
    Park, Han-A
    Licznerski, Pawel
    Li, Hongmei
    Nabili, Panah
    Hockensmith, Kathryn
    Graham, Morven
    Porter, George A., Jr.
    Jonas, Elizabeth A.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (29) : 10580 - 10585
  • [2] Potential role of subunit c of F0F1-ATPase and subunit c of storage body in the mitochondrial permeability transition. Effect of the phosphorylation status of subunit c on pore opening
    Azarashvili, Tamara
    Odinokova, Irina
    Bakunts, Anush
    Ternovsky, Vadim
    Krestinina, Olga
    Tyynelae, Jaana
    Saris, Nils-Erik Leo
    [J]. CELL CALCIUM, 2014, 55 (02) : 69 - 77
  • [3] Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I
    Batandier, C
    Leverve, X
    Fontaine, E
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (17) : 17197 - 17204
  • [4] The mitochondrial permeability transition pore: a mystery solved?
    Bernardi, Paolo
    [J]. FRONTIERS IN PHYSIOLOGY, 2013, 4
  • [5] Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition
    Carraro, Michela
    Giorgio, Valentina
    Sileikyte, Justina
    Sartori, Geppo
    Forte, Michael
    Lippe, Giovanna
    Zoratti, Mario
    Szabo, Ildiko
    Bernardi, Paolo
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (23) : 15980 - 15985
  • [6] Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
    Chouchani, Edward T.
    Pell, Victoria R.
    Gaude, Edoardo
    Aksentijevic, Dunja
    Sundier, Stephanie Y.
    Robb, Ellen L.
    Logan, Angela
    Nadtochiy, Sergiy M.
    Ord, Emily N. J.
    Smith, Anthony C.
    Eyassu, Filmon
    Shirley, Rachel
    Hu, Chou-Hui
    Dare, Anna J.
    James, Andrew M.
    Rogatti, Sebastian
    Hartley, Richard C.
    Eaton, Simon
    Costa, Ana S. H.
    Brookes, Paul S.
    Davidson, Sean M.
    Duchen, Michael R.
    Saeb-Parsy, Kourosh
    Shattock, Michael J.
    Robinson, Alan J.
    Work, Lorraine M.
    Frezza, Christian
    Krieg, Thomas
    Murphy, Michael P.
    [J]. NATURE, 2014, 515 (7527) : 431 - +
  • [7] Dimers of mitochondrial ATP synthase form the permeability transition pore
    Giorgio, Valentina
    von Stockum, Sophia
    Antoniel, Manuela
    Fabbro, Astrid
    Fogolari, Federico
    Forte, Michael
    Glick, Gary D.
    Petronilli, Valeria
    Zoratti, Mario
    Szabo, Ildiko
    Lippe, Giovanna
    Bernardi, Paolo
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (15) : 5887 - 5892
  • [8] MITOCHONDRIAL NONSPECIFIC PORES REMAIN CLOSED DURING CARDIAC ISCHEMIA, BUT OPEN UPON REPERFUSION
    GRIFFITHS, EJ
    HALESTRAP, AP
    [J]. BIOCHEMICAL JOURNAL, 1995, 307 : 93 - 98
  • [9] The mitochondrial permeability transition: A current perspective on its identity and role in ischaemia/reperfusion injury
    Halestrap, Andrew P.
    Richardson, Andrew P.
    [J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2015, 78 : 129 - 141
  • [10] Mitochondrial permeability transition pore opening during myocardial reperfusion - a target for cardioprotection
    Halestrap, AP
    Clarke, SJ
    Javadov, SA
    [J]. CARDIOVASCULAR RESEARCH, 2004, 61 (03) : 372 - 385
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