Radiologically isolated syndrome: An update on a rare entity

被引：16

作者：

Labiano-Fontcuberta, Andres ^{[1
]}

Benito-Leon, Julian ^{[1
,2
,3
]}

机构：

[1] Univ Hosp 12 Octubre, Dept Neurol, Avda Constituc 73,Portal 3,7 Izquierda, E-28821 Madrid, Spain

[2] Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

[3] Univ Complutense Madrid, Dept Med, Madrid, Spain

来源：

MULTIPLE SCLEROSIS JOURNAL | 2016年 / 22卷 / 12期

基金：

美国国家卫生研究院;

关键词：

Radiologically isolated syndrome; clinical; MRI; review; CLINICALLY ISOLATED SYNDROMES; REMITTING MULTIPLE-SCLEROSIS; COGNITIVE IMPAIRMENT; MATTER ATROPHY; WHITE-MATTER; CONVERSION; LESIONS; ABNORMALITIES; ASSOCIATION; DEPRESSION;

D O I：

10.1177/1352458516653666

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Our understanding of radiologically isolated syndrome (RIS) is evolving, as new data emerge on the clinical characterization and the pathophysiological nature of this rare entity. This topical review aims to (1) outline state-of-the-art clinical and magnetic resonance imaging findings of RIS research; (2) raise the main obstacles to RIS research; (3) discuss the most controversial issues of current RIS findings; and (4) highlight potential strategies for upcoming research studies.

引用

收藏

页码：1514 / 1521

页数：8

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