Potential role for statins in the treatment of chronic HCV infection

被引:4
作者
Zhu, Qianqian [1 ]
Han, Qunying [1 ]
Liu, Zhengwen [1 ]
机构
[1] Xi An Jiao Tong Univ, Affiliated Hosp 1, Sch Med, Dept Infect Dis, Xian 710061, Shaanxi Provinc, Peoples R China
关键词
chronic hepatitis C; direct-acting antiviral; host-targeting agent; IFN-; ribavirin; statin; treatment; CHRONIC HEPATITIS-C; VIRUS-RNA REPLICATION; PEGYLATED INTERFERON; COMBINATION THERAPY; ANTIVIRAL EFFICACY; PLUS RIBAVIRIN; GENOTYPE; 1B; OPEN-LABEL; FLUVASTATIN; RESISTANCE;
D O I
10.2217/fvl.13.70
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
引用
收藏
页码:727 / 729
页数:3
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共 20 条
[11]  
Malaguarnera M, 2011, HEPAT MON, V11, P92
[12]   Atorvastatin does not exhibit antiviral activity against HCV at conventional doses: A pilot clinical trial [J].
O'Leary, Jacqueline G. ;
Chan, Jessica L. ;
McMahon, Cory M. ;
Chung, Raymond T. .
HEPATOLOGY, 2007, 45 (04) :895-898
[13]   Open-label, ascending dose, prospective cohort study evaluating the antiviral efficacy of Rosuvastatin therapy in serum and lipid fractions in patients with chronic hepatitis C [J].
Patel, K. ;
Jhaveri, R. ;
George, J. ;
Qiang, G. ;
Kenedi, C. ;
Brown, K. ;
Cates, C. ;
Zekry, A. ;
Tillmann, H. L. ;
Elliott, L. ;
Kilaru, R. ;
Albrecht, J. ;
Conrad, A. ;
McHutchison, J. G. .
JOURNAL OF VIRAL HEPATITIS, 2011, 18 (05) :331-337
[14]   Boceprevir for Untreated Chronic HCV Genotype 1 Infection [J].
Poordad, Fred ;
McCone, Jonathan, Jr. ;
Bacon, Bruce R. ;
Bruno, Savino ;
Manns, Michael P. ;
Sulkowski, Mark S. ;
Jacobson, Ira M. ;
Reddy, K. Rajender ;
Goodman, Zachary D. ;
Boparai, Navdeep ;
DiNubile, Mark J. ;
Sniukiene, Vilma ;
Brass, Clifford A. ;
Albrecht, Janice K. ;
Bronowicki, Jean-Pierre ;
Colombato, L. ;
Curciarello, J. ;
Silva, M. ;
Tanno, H. ;
Terg, R. ;
Adler, M. ;
Langlet, P. ;
Lasser, L. ;
Nevens, F. ;
Anderson, F. ;
Bailey, R. ;
Bilodeau, M. ;
Cooper, C. ;
Feinman, S. V. ;
Heathcote, J. ;
Levstik, M. ;
Ramji, A. ;
Sherman, M. ;
Shafran, S. ;
Yoshida, E. ;
Achim, A. ;
Ben Ali, S. ;
Bigard, M-A. ;
Bonny, C. ;
Bourliere, M. ;
Boyer-Darrigrand, N. ;
Bronowicki, J-P. ;
Canva, V. ;
Couzigou, P. ;
De Ledinghen, V. ;
Guyader, D. ;
Hezode, C. ;
Larrey, D. ;
Latournerie, M. ;
Marcellin, P. .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (13) :1195-1206
[15]   Statin Therapy Improves Sustained Virologic Response Among Diabetic Patients With Chronic Hepatitis C [J].
Rao, Gowtham A. ;
Pandya, Prashant K. .
GASTROENTEROLOGY, 2011, 140 (01) :144-+
[16]   An Open Pilot Study Exploring the Efficacy of Fluvastatin, Pegylated Interferon and Ribavirin in Patients with Hepatitis C Virus Genotype 1b in High Viral Loads [J].
Sezaki, Hitomi ;
Suzuki, Fumitaka ;
Akuta, Norio ;
Yatsuji, Hiromi ;
Hosaka, Tetsuya ;
Kobayashi, Masahiro ;
Suzuki, Yoshiyuki ;
Arase, Yasuji ;
Ikeda, Kenji ;
Miyakawa, Yuzo ;
Kumada, Hiromitsu .
INTERVIROLOGY, 2009, 52 (01) :43-48
[17]   Pitavastatin enhances antiviral efficacy of standard pegylated interferon plus ribavirin in patients with chronic hepatitis C: A prospective randomized pilot study [J].
Shimada, Masahiko ;
Yoshida, Shuhei ;
Masuzaki, Ryota ;
Schuppan, Detlef .
JOURNAL OF HEPATOLOGY, 2012, 56 (01) :299-300
[18]   Statins and the Risk of Hepatocellular Carcinoma in Patients With Hepatitis C Virus Infection [J].
Tsan, Yu-Tse ;
Lee, Chang-Hsing ;
Ho, Wen-Chao ;
Lin, Meng-Hung ;
Wang, Jung-Der ;
Chen, Pau-Chung .
JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (12) :1514-1521
[19]   Identification of FBL2 as a geranylgeranylated required for hepatitis C cellular protein virus RNA replication [J].
Wang, CF ;
Gale, M ;
Keller, BC ;
Huang, H ;
Brown, MS ;
Goldstein, JL ;
Ye, J .
MOLECULAR CELL, 2005, 18 (04) :425-434
[20]   Statin therapy improves response to interferon alfa and ribavirin in chronic hepatitis C: A systematic review and meta-analysis [J].
Zhu, Qianqian ;
Li, Na ;
Han, Qunying ;
Zhang, Pingping ;
Yang, Cuiling ;
Zeng, Xiaoyan ;
Chen, Yanping ;
Lv, Yi ;
Liu, Xi ;
Liu, Zhengwen .
ANTIVIRAL RESEARCH, 2013, 98 (03) :373-379