The Reaction of N-Isocyaniminotriphenylphosphorane With Biacetyl in the Presence of (E)-Cinnamic Acids: Synthesis of Fully Substituted 1,3,4-Oxadiazole Derivatives via Intramolecular AZA-Wittig Reactions of in Situ Generated Iminophosphoranes

被引：18

作者：

Ramazani, Ali ^{[1
]}

Abdian, Behnaz ^{[1
]}

Nasrabadi, Fatemeh Zeinali ^{[1
]}

Rouhani, Morteza ^{[2
]}

机构：

[1] Univ Zanjan, Dept Chem, Zanjan, Iran

[2] Islamic Azad Univ, Zanjan Branch, Young Researchers Club, Zanjan, Iran

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2013年 / 188卷 / 05期

基金：

美国国家科学基金会;

关键词：

N-isocyaniminotriphenylphosphorane; biacetyl; (E)-cinnamic acid; 1; 3; 4-oxadiazole; aza-Wittig reaction; AROMATIC CARBOXYLIC-ACIDS; CATALYZED STEREOSELECTIVE CONVERSION; STABILIZED PHOSPHORUS YLIDES; POLYMER-SUPPORTED REAGENTS; ONE-POT SYNTHESIS; X-RAY-STRUCTURE; MULTICOMPONENT REACTIONS; 3-COMPONENT REACTION; EFFICIENT SYNTHESIS; SILICA-GEL;

D O I：

10.1080/10426507.2012.700351

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Reaction of N-isocyaniminotriphenylphosphorane with biacetyl in the presence of (E)-cinnamic acids proceeds smoothly at room temperature and under neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeds smoothly and straightforward under mild conditions and no side reactions are observed.

引用

页码：642 / 648

页数：7

共 52 条

[1] The Reaction of (N-Isocyanimino) triphenylphosphorane with (E)-3-Aryl-2-propenoic Acid Derivatives: One-Pot Synthesis of 2-[(E)-2-Aryl-1-ethenyl]-1,3,4-oxadiazoles via Intramolecular aza-Wittig Reaction [J].