Pediatric Intracranial Hypertension: a Current Literature Review

被引:28
作者
Aylward, Shawn C. [1 ]
Way, Amanda L. [2 ]
机构
[1] Ohio State Univ, Coll Med, Nationwide Childrens Hosp, Dept Neurol, 700 Childrens Dr, Columbus, OH 43205 USA
[2] Nationwide Childrens Hosp, Dept Ophthalmol, Columbus, OH USA
关键词
Pseudotumor cerebri; Intracranial hypertension; Pediatric; Papilledema; Headache; FLUID OPENING PRESSURE; PSEUDOTUMOR CEREBRI SYNDROME; OPTICAL COHERENCE TOMOGRAPHY; CEREBROSPINAL-FLUID; LUMBAR PUNCTURE; DEMYELINATING DISEASE; COGNITIVE IMPAIRMENT; TREATMENT TRIAL; NERVE HEAD; PAPILLEDEMA;
D O I
10.1007/s11916-018-0665-9
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Purpose of Review The purpose of this review is to provide an update on pediatric intracranial hypertension. Recent Findings The annual pediatric incidence is estimated at 0.63 per 100,000 in the USA and 0.71 per 100,000 in Britain. The Idiopathic Intracranial Hypertension Treatment Trial found improvement in visual fields, optical coherence tomography, Frisen grade, and quality of life with acetazolamide compared to placebo in adult patients, and these findings have been translated to the pediatric population. Summary Pediatric intracranial hypertension is a disorder that if left untreated can lead to poor quality of life and morbidity. There are no current treatment studies in pediatrics, but adult data suggests acetazolamide remains an acceptable first-line medication.
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页数:9
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