Multicellular spheroids model in oncology

被引：0

作者：

Chomyak, OG ^{[1
]}

Sidorenko, MV ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, Inst Cryobiol & Cryomed Problems, Kharkov, Ukraine

来源：

EXPERIMENTAL ONCOLOGY | 2001年 / 23卷 / 04期

关键词：

spheroid; tumor cells;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Characteristics of spheroids formed by cancer cells and the possibility of their use in experimental immunology and oncology were reviewed. Also the application of spheroids to the study of radiation and chemotherapy action on cancer cells was discussed.

引用

页码：236 / 241

页数：6

共 50 条

[21] High-throughput screening in multicellular spheroids for target discovery in the tumor microenvironment [J].

Calpe, Blaise ;

Kovacs, Werner J. .

EXPERT OPINION ON DRUG DISCOVERY, 2020, 15 (08) :955-967

[22] Intervertebral disc spheroids as an in vitro multicellular platform for recapitulating the microenvironment of intervertebral disc degeneration [J].

Kim, Tae-Won ;

Kim, An-Gi ;

Hwang, Min-Ho ;

Choi, Hyuk .

BIOFABRICATION, 2025, 17 (03)

[23] Enhancement of aberrantly modified integrin-mediated cell motility in multicellular tumor spheroids [J].

Kim, Byoungjae ;

Im, Nu-Ri ;

Yang, Taeseok Daniel ;

Kim, Jian ;

Jung, Kwang-Yoon ;

Kim, Tae Hoon ;

Baek, Seung-Kuk .

INTERNATIONAL JOURNAL OF ONCOLOGY, 2020, 56 (06) :1480-1489

[24] Simulating growth dynamics and radiation response of avascular tumour spheroids - model validation in the case of an EMT6/Ro multicellular spheroid [J].

Zacharaki, EI ;

Stamatakos, GS ;

Nikita, KS ;

Uzunoglu, NK .

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 2004, 76 (03) :193-206

[25] Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids [J].

Kusamori, Kosuke ;

Nishikawa, Makiya ;

Mizuno, Narumi ;

Nishikawa, Tomoko ;

Masuzawa, Akira ;

Tanaka, Yutaro ;

Mizukami, Yuya ;

Shimizu, Kazunori ;

Konishi, Satoshi ;

Takahashi, Yuki ;

Takakura, Yoshinobu .

PHARMACEUTICAL RESEARCH, 2016, 33 (01) :247-256

[26] 3D Printed Monolithic Device for the Microfluidic Capture, Perfusion, and Analysis of Multicellular Spheroids [J].

Markoski, Alex ;

Wong, Ian Y. ;

Borenstein, Jeffrey T. .

FRONTIERS IN MEDICAL TECHNOLOGY, 2021, 3

[27] Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids [J].

Kosuke Kusamori ;

Makiya Nishikawa ;

Narumi Mizuno ;

Tomoko Nishikawa ;

Akira Masuzawa ;

Yutaro Tanaka ;

Yuya Mizukami ;

Kazunori Shimizu ;

Satoshi Konishi ;

Yuki Takahashi ;

Yoshinobu Takakura .

Pharmaceutical Research, 2016, 33 :247-256

[28] Microfluidic Biofabrication of 3D Multicellular Spheroids by Modulation of Non-geometrical Parameters [J].

Lopan, Silvia ;

Piraino, Francesco ;

Talo, Giuseppe ;

Mainardi, Valerio Luca ;

Bersini, Simone ;

Pierro, Margherita ;

Zagra, Luigi ;

Rasponi, Marco ;

Moretti, Matteo .

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 8

[29] A quantitative metric for the comparative evaluation of optical clearing protocols for 3D multicellular spheroids [J].

Diosdi, Akos ;

Hirling, Dominik ;

Kovacs, Maria ;

Toth, Timea ;

Harmati, Maria ;

Koos, Krisztian ;

Buzas, Krisztina ;

Piccinini, Filippo ;

Horvath, Peter .

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 19 :1233-1243

[30] High-Efficiency Generation, Drug and Radiosensitivity Test of Multicellular Tumor Spheroids by a Novel Microdevice [J].

Ding, Siwei ;

Lu, Chunyang ;

Sun, Xiaoyi ;

Li, Tiancheng ;

Zhao, Ye ;

Yang, Gen .

CHEMOSENSORS, 2022, 10 (08)

← 1 2 3 4 5 →