Granulomatous reaction to red tattoo pigment treated with allopurinol

被引：24

作者：

Godinho, Mariana Marteleto ^{[1
,2
,3
]}

Aguinaga, Felipe ^{[1
,2
,3
]}

Grynszpan, Rachel ^{[1
,2
,3
]}

Lima, Victor Maselli ^{[4
]}

Azulay, David Rubem ^{[1
,2
,3
]}

Cuzzi, Tullia ^{[5
,6
,7
]}

Ramos-e-Silva, Marcia ^{[1
,2
,3
]}

Manela-Azulay, Monica ^{[1
,2
,3
]}

机构：

[1] Univ Fed Rio de Janeiro, Sect Dermatol, Rio De Janeiro, Brazil

[2] Univ Fed Rio de Janeiro, Postgrad Course Dermatol, Univ Hosp, Rio De Janeiro, Brazil

[3] Univ Fed Rio de Janeiro, Sch Med, Rio De Janeiro, Brazil

[4] Pontificia Univ Catolica Rio de Janeiro, Sect Plast Surg, Ivo Pitanguy Inst, Rio De Janeiro, Brazil

[5] Univ Fed Rio de Janeiro, Sect Pathol, Rio De Janeiro, Brazil

[6] Univ Fed Rio de Janeiro, Postgrad Course, Univ Hosp, Rio De Janeiro, Brazil

[7] Univ Fed Rio de Janeiro, Sch Med, Rio De Janeiro, Brazil

来源：

JOURNAL OF COSMETIC DERMATOLOGY | 2015年 / 14卷 / 03期

关键词：

allopurinol; tattoo; red pigment; granulomatous reaction; FOREIGN-BODY GRANULOMAS; GIANT-CELL FORMATION; XANTHINE-OXIDASE; FILLERS;

D O I：

10.1111/jocd.12149

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Granulomatous reactions to tattoo ink are most commonly associated with mercury sulfide, a component of red pigments. Treatment options show limited results. Allopurinol, an inhibitor of xanthine oxidase, has been reported as a successful alternative treatment to granulomatous disorders, such as sarcoidosis and granulomatous reactions to fillers and tattoos. We report a case of granulomatous reaction to red tattoo pigment treated with allopurinol for 6months. Good clinical improvement could be noticed during this time. Two months after we stopped the treatment, the lesion recurred. Allopurinol emerges as an important drug for the management of granulomatous reactions caused by tattoo pigments. Based on the significant clinical improvement noticed during its use, we recommend new studies to elucidate all the potential benefits of the use of allopurinol for the treatment of granulomatous reactions to tattoo ink.

引用

页码：241 / 245

页数：5

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