Cu(II) Schiff Base as Catalyst in the Synthesis of 1,8-Dioxodecahydroacridine

被引:15
作者
Vahdat, Seyed Mohammad [1 ]
Mardani, Hamid Reza [2 ]
Golchoubian, Hamid [3 ]
Khavarpour, Maryam [4 ]
Baghery, Saeed [5 ]
Roshankouhi, Ziba [5 ]
机构
[1] Islamic Azad Univ, Ayatollah Amoli Branch, Dept Chem, Amol, Iran
[2] PayameNoor Univ, Dept Chem, Tehran, Iran
[3] Univ Mazandaran, Dept Chem, Babol Sar, Iran
[4] Islamic Azad Univ, Ayatollah Amoli Branch, Dept Chem Engn, Amol, Iran
[5] Islamic Azad Univ, Ayatollah Amoli Branch, Amol, Iran
关键词
1,8-Dioxodecahydroacridine; Cu(II) Schiff-base catalyst; multi component reaction; one-pot synthesis; water solvent; ONE-POT SYNTHESIS; ACRIDINE-DERIVATIVES; AMBIENT-TEMPERATURE; IONIC LIQUID; 1,8-DIOXO-DECAHYDROACRIDINES; EFFICIENT; OXIDATION;
D O I
10.2174/1386207311316010002
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The catalytic property of Cu(II) Schiff-base complex in an efficient synthesis of 1,8-dioxodecahydroacridines was investigated. The one-pot three component reaction of dimedone, aromatic aldehydes and aromatic amines or ammonium acetate in water afforded the corresponding 1,8-dioxodecahydroacridines with excellent yields. This reaction was carried out in the presence of 1 mol% of catalysts at room temperature. The reusability of the catalysts was demonstrated by a five-run test without loss of its activity. Also, this catalyst possesses several advantages including mild reaction conditions, lower catalytic loading, shorter reaction times, high yield of the products, inexpensive and cleaner (Green chemistry) reactions.
引用
收藏
页码:2 / 6
页数:5
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