Gold nanoparticles: sonocatalytic synthesis using ethanolic extract of Andrographis paniculata and functionalization with polycaprolactone- gelatin composites

被引：20

作者：

Babu, Punuri Jayasekhar ^{[1
,2
]}

Saranya, Sibyala ^{[2
,3
]}

Sharma, Pragya ^{[2
]}

Tamuli, Ranjan ^{[2
]}

Bora, Utpal ^{[1
,2
]}

机构：

[1] Indian Inst Technol Guwahati, Dept Biotechnol, Biomat & Tissue Engn Lab, Gauhati 781039, Assam, India

[2] Indian Inst Technol Guwahati, Ctr Environm, Biotech Hub, Gauhati 781039, Assam, India

[3] DRW Coll, Dept Biotechnol, Sps Nellore 524101, Andhra Pradesh, India

来源：

FRONTIERS OF MATERIALS SCIENCE | 2012年 / 6卷 / 03期

关键词：

sonocatalasis; Andrographis paniculata; functionalization; crystal growth; biomaterial; PCL-GL composite; BIOLOGICAL SYNTHESIS; GREEN SYNTHESIS;

D O I：

10.1007/s11706-012-0175-3

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Gold nanoparticles (AuNPs) were synthesized by sonication using ethanolic leaf extract of Andrographis paniculata. We investigated the optimum parameters for AuNP synthesis and functionalization with polycaprolactone- gelatin (PCL-GL) composites. The AuNPs were characterized with various biophysical techniques such as TEM, XRD, FT-IR and EDX spectroscopy. TEM images showed that nanoparticles were spherical in shape with a size range from 5 to 75 nm. EDX analysis revealed the presence of molecular oxygen and carbon on the surface of AuNPs. The synthesized AuNPs were tested for their effect on HeLa (human cervical cancer) and MCF7 (human breast cancer) cell lines and found to be nontoxic and biocompatible, which are potential carriers for hydrophobic drugs.

引用

页码：236 / 249

页数：14

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