Luminescent Ruthenium(II) Polypyridine Complexes for a Wide Variety of Biomolecular and Cellular Applications

被引:131
作者
Shum, Justin [1 ]
Leung, Peter Kam-Keung [1 ]
Lo, Kenneth Kam-Wing [1 ,2 ,3 ]
机构
[1] City Univ Hong Kong, Dept Chem, Kowloon, Tat Chee Ave, Hong Kong, Peoples R China
[2] City Univ Hong Kong, State Key Lab Terahertz & Millimeter Waves, Kowloon, Tat Chee Ave, Hong Kong, Peoples R China
[3] City Univ Hong Kong, Ctr Funct Photon, Kowloon, Tat Chee Ave, Hong Kong, Peoples R China
基金
中国国家自然科学基金;
关键词
DNA-BINDING; PHOTODYNAMIC THERAPY; METAL-COMPLEXES; NITRIC-OXIDE; BIPYRIDYL COMPLEXES; HYPOCHLOROUS ACID; BIOTIN COMPLEXES; PROBES; PHOTOSENSITIZERS; MECHANISMS;
D O I
10.1021/acs.inorgchem.8b02979
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Ruthenium(II) polypyridine complexes are one of the most extensively studied and developed systems in the family of luminescent transition-metal complexes. Notably, there has been a large amount of interest in the biological applications of these luminescent ruthenium(II) complexes because of their rich photophysical and photochemical properties. In this Viewpoint, we explore past and recent works on the possible biological and cellular applications of these promising complexes, with a focus on their use as bioimaging reagents, biomolecular probes, and phototherapeutic agents.
引用
收藏
页码:2231 / 2247
页数:17
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