Synthesis of fluorine containing tetracyclic ring systems: 1,2,4-triazino[3',4',3,4][1,2,4]triazino[5,6-b]indole and 1,2-4-triazino[4',3':2,3][1,2,4]triazino[5,6-b]indole

被引：0
|
作者：
Dandia, A [1 ]
Ahmed, N [1 ]
Sehgal, V [1 ]
Saha, M [1 ]
机构：
[1] UNIV RAJASTHAN,DEPT CHEM,JAIPUR 302004,RAJASTHAN,INDIA
来源：
ASIAN JOURNAL OF CHEMISTRY | 1997年 / 9卷 / 03期
关键词：
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中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Tetracyclic ring systems viz. 2-methyl-1-oxo-11H-1,2,4-triazino [3',4':3,4] [1,2,4] triazino [5,6-b] indole (V) and 3-methyl-4-oxo-11H-1,2,4-triazino [4',3':2,3] [1,2,4] triazino [5,6-b] indole (VI) were synthesized by the cyclization of 2-oxo-propionic acid [5H-1,2,4-triazino] [5,6-b] indole-3-yl hydroazone (IV). Cyclization of (IVb) (X = 7-F) and (IVc) (X = 8-F) afforded the angular product (V) exclusively, while cyclization of IVa (no F) and IVd (X = 9-CF3) gave a mixture of angular (V) and linear products (VI) in-the ratio 3: 1. Compound (IV) was prepared from III on heating with sodium hydroxide in ethanol-water (50:50) while the hydrazide (III) was itself obtained by the condensation of 3-hydrazino dervatives (II) with ethyl pyruvate in absolute ethanol. The synthesised, compounds may prove to be effective pesticides also.
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页码：501 / 508
页数：8
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