Clinical and Epidemiological Features of 46 Children <1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study

被引：27

作者：

Liu, Xinghua ^{[1
]}

Tang, Jianqiao ^{[7
]}

Xie, Rong ^{[2
]}

Li, Wei ^{[1
]}

Chen, Jianying ^{[1
]}

Guo, Yan ^{[3
]}

Zhang, Bo ^{[2
]}

Zhang, Yue ^{[2
]}

Wang, Juanjuan ^{[4
]}

Peng, Cao ^{[5
]}

Lei, Xiao ^{[6
]}

Luo, Qunying ^{[6
]}

Zhang, Qiong ^{[6
]}

Li, Yunqiao ^{[6
]}

机构：

[1] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Gastrointestinal Surg, Wuhan, Peoples R China

[2] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Thyroid & Breast Surg, Wuhan, Peoples R China

[3] Wuhan Ctr Dis Control & Prevent, Wuhan, Peoples R China

[4] Anhui Prov Childrens Hosp, Dept Rheumatol & Immunol, Hefei, Peoples R China

[5] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Emergency Med, Wuhan, Peoples R China

[6] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Gen Practice, 1277 JieFang Ave, Wuhan 430022, Peoples R China

[7] Huazhong Univ Sci & Technol, Wuhan Childrens Hosp, Tongji Mod Coll, Dept Pediat, Wuhan, Peoples R China

来源：

JOURNAL OF INFECTIOUS DISEASES | 2020年 / 222卷 / 08期

基金：

中国国家自然科学基金;

关键词：

children; clinical features; SARS-CoV-2; outcome;

D O I：

10.1093/infdis/jiaa472

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The number of coronavirus disease 2019 (COVID-19) cases has exceeded 10 million. However, little is known about the epidemiology and clinical characteristics of COVID-19 infants. We collected medical information of 46 confirmed patients (<1 year old) and retrospectively analyzed epidemiological history, clinical symptoms, and laboratory test results. The median age was 5 (interquartile range, 2-7) months. Sixteen cases had fever and 27 cases had cough. Moderate disease was present in 40 cases and cardiac injury occurred in 38 cases, following by liver dysfunction in 20 cases and lymphocytosis in no cases. Of all infant patients, 2 received invasive mechanical ventilation and 1 died with multiple organ dysfunction syndrome.

引用

页码：1293 / 1297

页数：5

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Clinical and Epidemiological Features of 46 Children &lt;1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study

Clinical and Epidemiological Features of 46 Children <1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study