Activation of ERK1/2 is required for the antimitotic activity of theresveratrol analogue 3,4,5,4-tetramethoxystilbene (DMU-212) in human melanoma cells

被引:22
作者
Androutsopoulos, Vasilis Pericles [1 ]
Fragiadaki, Irene [1 ]
Tosca, Androniki [1 ]
机构
[1] Univ Crete, Sch Med, Lab Expt Dermatol, Iraklion 71003, Crete, Greece
关键词
resveratrol-antimitotic-apoptosis-cell cycle-stilbenes-ERK; TRANS 3,4,5,4'-TETRAMETHOXYSTILBENE DMU-212; CHEMOPREVENTIVE AGENT RESVERATROL; G(2)/M TRANSITION; CANCER-CELLS; APOPTOSIS; GROWTH; CYCLE; MECHANISM;
D O I
10.1111/exd.12721
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:632 / 634
页数:3
相关论文
共 15 条
[1]   Anticancer effects of the metabolic products of the resveratrol analogue, DMU-212: Structural requirements for potency [J].
Androutsopoulos, Vasilis P. ;
Ruparelia, Ketan C. ;
Papakyriakou, Athanasios ;
Filippakis, Harilaos ;
Tsatsakis, Aristeidis M. ;
Spandidos, Demetrios A. .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 46 (06) :2586-2595
[2]   Chemoprevention of photocarcinogenesis by lycopene [J].
Ascenso, Andreia ;
Ribeiro, Helena ;
Marques, Helena C. ;
Oliveira, Helena ;
Santos, Conceicao ;
Simoes, Sandra .
EXPERIMENTAL DERMATOLOGY, 2014, 23 (12) :874-878
[3]   Resveratrol-induced inactivation of human gastric adenocarcinoma cells through a protein kinase C-mediated mechanism [J].
Atten, MJ ;
Attar, BM ;
Milson, T ;
Holian, O .
BIOCHEMICAL PHARMACOLOGY, 2001, 62 (10) :1423-1432
[4]   Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012 [J].
Ferlay, J. ;
Steliarova-Foucher, E. ;
Lortet-Tieulent, J. ;
Rosso, S. ;
Coebergh, J. W. W. ;
Comber, H. ;
Forman, D. ;
Bray, F. .
EUROPEAN JOURNAL OF CANCER, 2013, 49 (06) :1374-1403
[5]   Raf-1/MEK/MAPK pathway is necessary for the G2/M transition induced by nocodazole [J].
Hayne, C ;
Tzivion, G ;
Luo, ZJ .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (41) :31876-31882
[6]   Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression [J].
Ivanov, Vladimir N. ;
Partridge, Michael A. ;
Johnson, Geoffrey E. ;
Huang, Sarah X. L. ;
Zhou, Hongning ;
Hei, Tom K. .
EXPERIMENTAL CELL RESEARCH, 2008, 314 (05) :1163-1176
[7]   Cancer chemopreventive activity of resveratrol, a natural product derived from grapes [J].
Jang, MS ;
Cai, EN ;
Udeani, GO ;
Slowing, KV ;
Thomas, CF ;
Beecher, CWW ;
Fong, HHS ;
Farnsworth, NR ;
Kinghorn, AD ;
Mehta, RG ;
Moon, RC ;
Pezzuto, JM .
SCIENCE, 1997, 275 (5297) :218-220
[8]   Resveratrol analog trans 3,4,5,4′-tetramethoxystilbene (DMU-212) mediates anti-tumor effects via mechanism different from that of resveratrol [J].
Ma, Zengshuan ;
Molavi, Ommoleila ;
Haddadi, Azita ;
Lai, Raymond ;
Gossage, Robert A. ;
Lavasanifar, Afsaneh .
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2008, 63 (01) :27-35
[9]   Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells -: art. no. 27 [J].
Mahyar-Roemer, M ;
Köhler, H ;
Roemer, K .
BMC CANCER, 2002, 2 (1)
[10]   Resveratrol analogue 3,4,4′,5-tetramethoxystilbene inhibits growth, arrests cell cycle and induces apoptosis in ovarian SKOV-3 and A-2780 cancer cells [J].
Piotrowska, Hanna ;
Myszkowski, Krzysztof ;
Ziolkowska, Alicja ;
Kulcenty, Katarzyna ;
Wierzchowski, Marcin ;
Kaczmarek, Mariusz ;
Murias, Marek ;
Kwiatkowska-Borowczyk, Eliza ;
Jodynis-Liebert, Jadwiga .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 263 (01) :53-60