Study of receptor mediated selective anion transmembrane transport using parallel artificial membrane permeability assay

被引：2
作者：
Veverkova, Lenka [1 ]
Zaruba, Kamil [1 ]
Kral, Vladimir [1 ,2 ]
机构：
[1] Inst Chem Technol, Dept Analyt Chem, CR-16628 Prague 6, Czech Republic
[2] Zentiva Dev, Prague 10237 10, Czech Republic
来源：
ANALYST | 2013年 / 138卷 / 10期
关键词：
PAMPA; PUMP;
D O I：
10.1039/c3an36760f
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The separation performance of inorganic anions ReO4-, Br-, SO42-, and NO3- using porphyrin-alkaloid quaternary salt transporters is examined using parallel artificial membrane permeability assay. Active and selective transport of perrhenate is achieved by porphyrin-brucine conjugates. Herein, chlorides are used as anti-porters and complete removal of perrhenates from a source solution is stimulated due to electrostatic effects.
引用
收藏
页码：2804 / 2807
页数：4
相关论文
共 26 条
[1]   PAMPA - A drug absorption in vitro model 13. Chemical selectivity due to membrane hydrogen bonding: In combo comparisons of HDM-, DOPC-, and DS-PAMPA models [J].
Avdeef, A ;
Tsinman, O .
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2006, 28 (1-2) :43-50
[2]   PAMPA - Critical factors for better predictions of absorption [J].
Avdeef, Alex ;
Bendels, Stefanie ;
Di, Li ;
Faller, Bernard ;
Kansy, Manfred ;
Sugano, Kiyohiko ;
Yamauchi, Yukinori .
JOURNAL OF PHARMACEUTICAL SCIENCES, 2007, 96 (11) :2893-2909
[3]   Anion binding and transport by steroid-based receptors [J].
Davis, Anthony P. .
COORDINATION CHEMISTRY REVIEWS, 2006, 250 (23-24) :2939-2951
[4]   Octafluorocalix[4]pyrrole: A Chloride/Bicarbonate Antiport Agent [J].
Gale, Philip A. ;
Tong, Christine C. ;
Haynes, Cally J. E. ;
Adeosun, Olubukunola ;
Gross, Dustin E. ;
Karnas, Elizabeth ;
Sedenberg, Elaine M. ;
Quesada, Roberto ;
Sessler, Jonathan L. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (10) :3240-+
[5]   Is PAMPA a useful too for discovery? [J].
Galinis-Luciani, D. ;
Nguyen, L. ;
Yazdanian, M. .
JOURNAL OF PHARMACEUTICAL SCIENCES, 2007, 96 (11) :2886-2892
[6]   Monoprotonated sapphyrin-pertechnetate anion interactions in aqueous media [J].
Gorden, AEV ;
Davis, J ;
Sessler, JL ;
Král, V ;
Keogh, DW ;
Schroeder, NL .
SUPRAMOLECULAR CHEMISTRY, 2004, 16 (02) :91-100
[7]   Transmembrane anion transport by synthetic systems [J].
Haynes, Cally J. E. ;
Gale, Philip A. .
CHEMICAL COMMUNICATIONS, 2011, 47 (29) :8203-8209
[8]   The role of inorganic chemistry in the development of radiometal agents for cancer therapy [J].
Heeg, MJ ;
Jurisson, SS .
ACCOUNTS OF CHEMICAL RESEARCH, 1999, 32 (12) :1053-1060
[9]   Cationic calix[4] arenes as anion-selective ionophores [J].
Izzo, Irene ;
Licen, Sabina ;
Maulucci, Nakia ;
Autore, Giuseppina ;
Marzocco, Stefania ;
Tecilla, Paolo ;
De Riccardis, Francesco .
CHEMICAL COMMUNICATIONS, 2008, (26) :2986-2988
[10]  
Jarvis S. M., 2000, MEMBRANE TRANSPORT P
123