Stereoselective synthesis of enantiomerically pure inherently chiral p-tert-butylcalix[4]arene carboxylic acids

被引：12

作者：

Karpus, Andrii O. ^{[1
,2
]}

Yesypenko, Oleksandr A. ^{[1
]}

Andronov, Leonid P. ^{[1
,3
]}

Boyko, Vyacheslav I. ^{[1
]}

Garasevich, Sergei G. ^{[3
]}

Voitenko, Zoia V. ^{[2
]}

Chernega, Alexander N. ^{[1
]}

Kalchenko, Vitaly I. ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, Inst Organ Chem, UA-9402660 Kiev, Ukraine

[2] Kiev Natl Taras Shevchenko Univ, Dept Chem, UA-01033 Kiev, Ukraine

[3] Kiev Natl Taras Shevchenko Univ, Dept Phys, UA-01033 Kiev, Ukraine

来源：

TETRAHEDRON-ASYMMETRY | 2012年 / 23卷 / 17期

关键词：

OPTICAL RESOLUTION; LOWER RIM; RECOGNITION; CALIXARENES; CONE;

D O I：

10.1016/j.tetasy.2012.07.016

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Both enantiomers of inherently chiral dipropoxy-p-tert-butylcalix[4],arene carboxylic acids with AABH substitution patterns have been prepared by the stereoselective reactions of 25,26-dipropoxy-p-tert-butylcalix[4]arene with enantiomerically pure (S)- or (R)-N-(1-phenylethyl)bromoacetamide, separation of the diastereomers by recrystallization, and removal of the chiral auxiliary groups. The absolute configurations of the obtained compounds have been established by X-ray analysis. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1243 / 1250

页数：8

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