Copper(I)-catalyzed tandem reaction of 2-iodophenols with isothiocyanates in room temperature ionic liquids

被引：5

作者：

Yao, Fang ^{[1
,2
]}

Hao, Wenyan ^{[1
]}

Cai, Ming-Zhong ^{[1
]}

机构：

[1] Jiangxi Normal Univ, Dept Chem, Nanchang 330022, Peoples R China

[2] Zhejiang Univ Technol, Dept Chem & Pharmaceut Engn, West Branch, Quzhou 324000, Peoples R China

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2013年 / 723卷

基金：

中国国家自然科学基金;

关键词：

Copper(I) catalysis; 2-Iminobenzo-1,3-oxathiole; Tandem reaction; Ionic liquid; 2-Iodophenol; OXATHIOLONE FUSED CHALCONES; CANCER-CELLS LINE; ONE-POT SYNTHESIS; RECYCLABLE CATALYST; COUPLING REACTIONS; HIGHLY EFFICIENT; CARBENE COMPLEX; DOMINO-REACTION; HECK REACTION; SOLVENTS;

D O I：

10.1016/j.jorganchem.2012.09.010

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A copper(I)-catalyzed tandem reaction of 2-iodophenols with isothiocyanates in hydrophobic [ bmim] [PF6] ionic liquid was described, which proceeded smoothly and generated a variety of 2-iminobenzo-1,3-oxathioles in good to excellent yields. The tandem reaction that was carried out in [ bmim][ PF6] has some obvious advantages such as reaction rate acceleration and yield increasing as compared with the reaction run in volatile solvents such as toluene. Furthermore, the CuI/1,10-phenanthroline catalytic system can be reused up to 6 times without loss of activity and efficiency. (C) 2012 Elsevier B. V. All rights reserved.

引用

页码：137 / 142

页数：6

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